4QM1

Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase with an Internal Deletion of the CBS Domain from Bacillus anthracis str. Ames complexed with inhibitor D67

Replaces:  4MXS

Summary for 4QM1

• Entry DOI: 10.2210/pdb4qm1/pdb
• Related: 3TSB 3TSD 3USB 4MJM
• Descriptor: Inosine-5'-monophosphate dehydrogenase, INOSINIC ACID, 2-(3-methyl-4-oxo-3,4-dihydrophthalazin-1-yl)-N-(6,7,8,9-tetrahydrodibenzo[b,d]furan-2-yl)acetamide, ... (4 entities in total)
• Functional Keywords: structural genomics, niaid, national institute of allergy and infectious diseases, center for structural genomics of infectious diseases, csgid, tim barrel, alpha-beta structure, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Bacillus anthracis (anthrax,anthrax bacterium); More
• Total number of polymer chains: 4
• Total formula weight: 165780.84

Authors

Kim, Y.,Makowska-Grzyska, M.,Gu, M.,Mandapati, K.,Gollapalli, D.,Gorla, S.K.,Zhang, M.,Hedstrom, L.,Anderson, W.F.,Joachimiak, A.,CSGID,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2014-06-14, release date: 2014-07-23, Last modification date: 2023-09-20)

• Primary citation: Kim, Y.,Makowska-Grzyska, M.,Gu, M.,Mandapati, K.,Gollapalli, D.,Gorla, S.K.,Zhang, M.,Hedstrom, L.,Anderson, W.F.,Joachimiak, A.,CSGID; Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase with an Internal Deletion of the CBS Domain from Bacillus anthracis str. Ames complexed with inhibitor D67; To be Published, 2014

Experimental method

X-RAY DIFFRACTION (2.7964 Å)