7KOA

Room Temperature Structure of SARS-CoV-2 Nsp10/16 Methyltransferase in a Complex with Cap-0 and SAM Determined by Pink-Beam Serial Crystallography

Summary for 7KOA

Related7JHE 7JPE 6XKM 6W4H 6WJT 6WKQ 6WQ3 6WVN 6WRZ
Descriptor2'-O-methyltransferase, Non-structural protein 10, P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, ... (6 entities in total)
Functional Keywordssars cov-2, serial crystallography, methyltransferase, m7gpppa, cap-0, s-adenosylhomometionine, structural genomics, center for structural genomics of infectious diseases, csgid, viral protein
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
Total number of polymer chains2
Total molecular weight50806.83
Authors
Primary citation
Wilamowski, M.,Sherrell, D.A.,Minasov, G.,Shuvalova, L.,Lavens, A.,Henning, R.,Maltseva, N.,Rosas-Lemus, M.,Kim, Y.,Satchell, K.J.F.,Srajer, V.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID)
Room Temperature Structure of SARS-CoV-2 Nsp10/Nsp16 Methyltransferase in a Complex with Cap-0 and SAM Determined by Pink-Beam Serial Crystallography
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.4 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.27330 0.3% 1.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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171588
PDB entries from 2020-11-25