7KOA
Room Temperature Structure of SARS-CoV-2 Nsp10/16 Methyltransferase in a Complex with Cap-0 and SAM Determined by Pink-Beam Serial Crystallography
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 2'-O-methyltransferase | polymer | 301 | 33627.5 | 1 | UniProt (P0DTD1) Pfam (PF06460) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | Non-structural protein 16 |
| 2 | B (B) | Non-structural protein 10 | polymer | 142 | 15075.2 | 1 | UniProt (P0DTD1) Pfam (PF09401) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | |
| 3 | C, E (A) | P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE | non-polymer | 787.4 | 2 | Chemie (GTA) | |||
| 4 | D (A) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) | |||
| 5 | F, G (B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | H, I (A, B) | water | water | 18.0 | 182 | Chemie (HOH) |
Sequence modifications
A: 1 - 298 (UniProt: P0DTD1)
B: 1 - 139 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 48702.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 2104.1 | |
| All* | Total formula weight | 50806.8 |
