7KMA
Crystal structure of eif2Balpha with a ligand.
Summary for 7KMA
Entry DOI | 10.2210/pdb7kma/pdb |
Related | 3ECS |
Descriptor | Translation initiation factor eIF-2B subunit alpha, 6-O-phosphono-alpha-D-mannopyranose, ACETATE ION, ... (4 entities in total) |
Functional Keywords | translation initiation factor eif-2b, translation factor activity, rna binding, translation regulator activity, nucleic acid binding, sugar binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 8 |
Total formula weight | 279444.92 |
Authors | Nocek, B.,Hao, Q.,Remarcik, C.,Stoll, V.,Wong, Y.,Sidrauski, C. (deposition date: 2020-11-02, release date: 2021-07-21, Last modification date: 2023-10-18) |
Primary citation | Hao, Q.,Heo, J.M.,Nocek, B.P.,Hicks, K.G.,Stoll, V.S.,Remarcik, C.,Hackett, S.,LeBon, L.,Jain, R.,Eaton, D.,Rutter, J.,Wong, Y.L.,Sidrauski, C. Sugar phosphate activation of the stress sensor eIF2B. Nat Commun, 12:3440-3440, 2021 Cited by PubMed: 34103529DOI: 10.1038/s41467-021-23836-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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