7JIB

Room Temperature Crystal Structure of Nsp10/Nsp16 from SARS-CoV-2 with Substrates and Products of 2'-O-methylation of the Cap-1

Summary for 7JIB

• Entry DOI: 10.2210/pdb7jib/pdb
• Related: 6W4H 6WJT 6WKQ 6WQ3 6WRZ 6WVN 6XKM 7JHE
• Descriptor: 2'-O-methyltransferase, Non-structural protein 10, CHLORIDE ION, ... (10 entities in total)
• Functional Keywords: sars cov-2, methyltransferase, m7gpppa, cap-0, cap-1, sah, sam, structural genomics, center for structural genomics of infectious diseases, csgid, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 2
• Total formula weight: 51814.39

Authors

Wilamowski, M.,Minasov, G.,Kim, Y.,Sherrell, D.A.,Shuvalova, L.,Lavens, A.,Chard, R.,Rosas-Lemus, M.,Maltseva, N.,Jedrzejczak, R.,Michalska, K.,Satchell, K.J.F.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2020-07-23, release date: 2020-08-26, Last modification date: 2023-10-18)

• Primary citation: Wilamowski, M.,Sherrell, D.A.,Minasov, G.,Kim, Y.,Shuvalova, L.,Lavens, A.,Chard, R.,Maltseva, N.,Jedrzejczak, R.,Rosas-Lemus, M.,Saint, N.,Foster, I.T.,Michalska, K.,Satchell, K.J.F.,Joachimiak, A.; 2'-O methylation of RNA cap in SARS-CoV-2 captured by serial crystallography.; Proc.Natl.Acad.Sci.USA, 118:-, 2021; PubMed: 33972410; DOI: 10.1073/pnas.2100170118

Experimental method

X-RAY DIFFRACTION (2.65 Å)