7E14

Compound2_GLP-1R_OWL833_Gs complex structure

Summary for 7E14

Entry DOI	10.2210/pdb7e14/pdb
EMDB information	30936
Descriptor	Gs, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, G protein, ... (8 entities in total)
Functional Keywords	ago-allosteric modulation of glp-1r, membrane protein
Biological source	Homo sapiens More
Total number of polymer chains	5
Total formula weight	142599.17
Authors	Cong, Z.T.,Chen, L.N.,Ma, H.L.,Yang, D.H.,Xu, H.E.,Zhang, Y.,Wang, M.W. (deposition date: 2021-01-30, release date: 2021-07-07, Last modification date: 2024-03-27)
Primary citation	Cong, Z.,Chen, L.N.,Ma, H.,Zhou, Q.,Zou, X.,Ye, C.,Dai, A.,Liu, Q.,Huang, W.,Sun, X.,Wang, X.,Xu, P.,Zhao, L.,Xia, T.,Zhong, W.,Yang, D.,Eric Xu, H.,Zhang, Y.,Wang, M.W. Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor. Nat Commun, 12:3763-3763, 2021 Cited by PubMed: 34145245 DOI: 10.1038/s41467-021-24058-z PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.9 Å)

Structure validation