7CFT

Cryo-EM strucutre of human acid-sensing ion channel 1a in complex with snake toxin Mambalgin1 at pH 8.0

Summary for 7CFT

Entry DOI	10.2210/pdb7cft/pdb
Related	7CFS
EMDB information	30347
Descriptor	Acid-sensing ion channel 1, Mambalgin-1, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	asic, human, mambalgin1 toxin, cryo-em structure, membrane protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	6
Total formula weight	185155.07
Authors	Sun, D.M.,Liu, S.L.,Li, S.Y.,Yang, F.,Tian, C.L. (deposition date: 2020-06-28, release date: 2020-10-21)
Primary citation	Sun, D.,Liu, S.,Li, S.,Zhang, M.,Yang, F.,Wen, M.,Shi, P.,Wang, T.,Pan, M.,Chang, S.,Zhang, X.,Zhang, L.,Tian, C.,Liu, L. Structural insights into human acid-sensing ion channel 1a inhibition by snake toxin mambalgin1. Elife, 9:-, 2020 Cited by PubMed: 32915133 DOI: 10.7554/eLife.57096 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.9 Å)

Structure validation