7CFS
Cryo-EM strucutre of human acid-sensing ion channel 1a at pH 8.0
Summary for 7CFS
Entry DOI | 10.2210/pdb7cfs/pdb |
EMDB information | 30346 |
Descriptor | Acid-sensing ion channel 1, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... (4 entities in total) |
Functional Keywords | asic, human, resting state, cryo-em structure, membrane protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 3 |
Total formula weight | 166914.31 |
Authors | Sun, D.M.,Liu, S.L.,Li, S.Y.,Yang, F.,Tian, C.L. (deposition date: 2020-06-28, release date: 2020-10-21) |
Primary citation | Sun, D.,Liu, S.,Li, S.,Zhang, M.,Yang, F.,Wen, M.,Shi, P.,Wang, T.,Pan, M.,Chang, S.,Zhang, X.,Zhang, L.,Tian, C.,Liu, L. Structural insights into human acid-sensing ion channel 1a inhibition by snake toxin mambalgin1. Elife, 9:-, 2020 Cited by PubMed: 32915133DOI: 10.7554/eLife.57096 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.56 Å) |
Structure validation
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