7CFS
Cryo-EM strucutre of human acid-sensing ion channel 1a at pH 8.0
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Acid-sensing ion channel 1 | polymer | 477 | 54701.3 | 3 | UniProt (P78348) Pfam (PF00858) | Homo sapiens (Human) | ASIC1,Amiloride-sensitive cation channel 2,neuronal,Brain sodium channel 2,BNaC2 |
| 2 | D, E, H, I, K... (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 3 | F, J, M (A, B, C) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 3 | Chemie (Y01) | |||
| 4 | G (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) |
Sequence modifications
A, B, C: 1 - 468 (UniProt: P78348)
| PDB | External Database | Details |
|---|---|---|
| Met -8 | - | initiating methionine |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 164103.9 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2810.4 | |
| All* | Total formula weight | 166914.3 |
