7CFS

Cryo-EM strucutre of human acid-sensing ion channel 1a at pH 8.0

Summary for 7CFS

Entry DOI	10.2210/pdb7cfs/pdb
EMDB information	30346
Descriptor	Acid-sensing ion channel 1, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... (4 entities in total)
Functional Keywords	asic, human, resting state, cryo-em structure, membrane protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	3
Total formula weight	166914.31
Authors	Sun, D.M.,Liu, S.L.,Li, S.Y.,Yang, F.,Tian, C.L. (deposition date: 2020-06-28, release date: 2020-10-21)
Primary citation	Sun, D.,Liu, S.,Li, S.,Zhang, M.,Yang, F.,Wen, M.,Shi, P.,Wang, T.,Pan, M.,Chang, S.,Zhang, X.,Zhang, L.,Tian, C.,Liu, L. Structural insights into human acid-sensing ion channel 1a inhibition by snake toxin mambalgin1. Elife, 9:-, 2020 Cited by PubMed: 32915133 DOI: 10.7554/eLife.57096 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.56 Å)

Structure validation