7SI0
IgE-Fc in complex with 813
Summary for 7SI0
Entry DOI | 10.2210/pdb7si0/pdb |
Related | 7SHT 7SHU 7SHY 7SHZ |
Descriptor | IgE Fc, 813 Variable fragment Heavy chain, 813 Variable fragment Light chain, ... (8 entities in total) |
Functional Keywords | ige, omalizumab, xolair, inhibitor, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 12 |
Total formula weight | 226328.11 |
Authors | Pennington, L.F.,Jardetzky, T.J.,Kleinboelting, S. (deposition date: 2021-10-12, release date: 2021-12-15, Last modification date: 2023-10-18) |
Primary citation | Pennington, L.F.,Gasser, P.,Kleinboelting, S.,Zhang, C.,Skiniotis, G.,Eggel, A.,Jardetzky, T.S. Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex. Nat Commun, 12:7069-7069, 2021 Cited by PubMed: 34862384DOI: 10.1038/s41467-021-27397-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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