7SHZ
IgE-Fc in complex with HAE
Summary for 7SHZ
Entry DOI | 10.2210/pdb7shz/pdb |
Related | 7SHT 7SHU 7SHY |
Descriptor | IgE Fc, 1,2-ETHANEDIOL, alpha-D-mannopyranose, ... (13 entities in total) |
Functional Keywords | ige, omalizumab, xolair, inhibitor, immune system, e27 |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 12 |
Total formula weight | 227152.66 |
Authors | Pennington, L.F.,Jardetzky, T.J.,Kleinboelting, S. (deposition date: 2021-10-11, release date: 2021-12-22, Last modification date: 2024-10-16) |
Primary citation | Pennington, L.F.,Gasser, P.,Kleinboelting, S.,Zhang, C.,Skiniotis, G.,Eggel, A.,Jardetzky, T.S. Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex. Nat Commun, 12:7069-7069, 2021 Cited by PubMed: 34862384DOI: 10.1038/s41467-021-27397-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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