7SI0
IgE-Fc in complex with 813
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F, G, H (B, G, H, A) | IgE Fc | polymer | 247 | 27550.9 | 4 | UniProt (P01854) Pfam (PF07654) | Homo sapiens (Human) | Immunoglobulin heavy constant epsilon, Ig epsilon chain C region,Ig epsilon chain C region ND |
| 2 | B, D, I, K (I, E, C, K) | 813 Variable fragment Heavy chain | polymer | 123 | 13463.8 | 4 | Homo sapiens | ||
| 3 | C, E, J, L (J, F, D, L) | 813 Variable fragment Light chain | polymer | 134 | 14589.7 | 4 | Homo sapiens | ||
| 4 | M, O, P (M, O, P) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 3 | In PDB GlyTouCan (G81315DD) | |||
| 5 | N, Q (N, Q) | alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose | branched | 342.3 | 2 | In PDB GlyTouCan (G77384RA) | |||
| 6 | R (R) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 7 | S, T, U (I, E, K) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 8 | AA, BA, CA, V, W... (D, K, L, B, J...) | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence modifications
B, G, H, A: 328 - 545 (UniProt: P01854)
| PDB | External Database | Details |
|---|---|---|
| Ala 299 | - | expression tag |
| Pro 300 | - | expression tag |
| Met 301 | - | expression tag |
| Ala 302 | - | expression tag |
| Glu 303 | - | expression tag |
| Gly 304 | - | expression tag |
| Gly 305 | - | expression tag |
| Gly 306 | - | expression tag |
| Gln 307 | - | expression tag |
| Asn 308 | - | expression tag |
| His 309 | - | expression tag |
| His 310 | - | expression tag |
| His 311 | - | expression tag |
| His 312 | - | expression tag |
| His 313 | - | expression tag |
| His 314 | - | expression tag |
| His 315 | - | expression tag |
| His 316 | - | expression tag |
| Gly 317 | - | expression tag |
| Gly 318 | - | expression tag |
| Glu 319 | - | expression tag |
| Asn 320 | - | expression tag |
| Leu 321 | - | expression tag |
| Tyr 322 | - | expression tag |
| Phe 323 | - | expression tag |
| Gln 324 | - | expression tag |
| Gly 325 | - | expression tag |
| Gly 326 | - | expression tag |
| Ser 327 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 222417.7 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 3841.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 69.0 | |
| All* | Total formula weight | 226328.1 |
