7KD6
Insulin Receptor L1-CR plus alphaCT fragment in co-complex with Fv 83-7 and single-chain insulin SCI-b
Summary for 7KD6
Entry DOI | 10.2210/pdb7kd6/pdb |
Related | 6VEP |
Descriptor | Single-chain Insulin SCI-b, GLYCEROL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total) |
Functional Keywords | insulin receptor single-chain insulin antibody fv module insulin micro-receptor, signaling protein |
Biological source | Homo sapiens More |
Total number of polymer chains | 20 |
Total formula weight | 295389.59 |
Authors | Lawrence, M.C.,Menting, J.G. (deposition date: 2020-10-08, release date: 2021-10-13, Last modification date: 2024-10-09) |
Primary citation | Smith, N.A.,Menting, J.G.,Weiss, M.A.,Lawrence, M.C.,Smith, B.J. Single-chain insulin analogs threaded by the insulin receptor alpha CT domain. Biophys.J., 2022 Cited by PubMed: 36181268DOI: 10.1016/j.bpj.2022.09.038 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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