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7KD6

Insulin Receptor L1-CR plus alphaCT fragment in co-complex with Fv 83-7 and single-chain insulin SCI-b

Functional Information from GO Data
ChainGOidnamespacecontents
B0005179molecular_functionhormone activity
B0005576cellular_componentextracellular region
H0005179molecular_functionhormone activity
H0005576cellular_componentextracellular region
N0005179molecular_functionhormone activity
N0005576cellular_componentextracellular region
T0005179molecular_functionhormone activity
T0005576cellular_componentextracellular region
Functional Information from PROSITE/UniProt
site_idPS00262
Number of Residues15
DetailsINSULIN Insulin family signature. CCHSiCSleqLenyC
ChainResidueDetails
BCYS42-CYS56

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsSITE: Insulin-binding => ECO:0000305
ChainResidueDetails
EPHE39
KPHE39
QPHE39
WPHE39

site_idSWS_FT_FI2
Number of Residues4
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16894147, ECO:0000269|PubMed:23302862, ECO:0000269|PubMed:2983222
ChainResidueDetails
EASN16
KASN16
QASN16
WASN16

site_idSWS_FT_FI3
Number of Residues12
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16894147, ECO:0000269|PubMed:23302862
ChainResidueDetails
EASN25
WASN25
WASN111
WASN255
EASN111
EASN255
KASN25
KASN111
KASN255
QASN25
QASN111
QASN255

site_idSWS_FT_FI4
Number of Residues8
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
EASN78
EASN295
KASN78
KASN295
QASN78
QASN295
WASN78
WASN295

site_idSWS_FT_FI5
Number of Residues4
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16894147, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:23302862
ChainResidueDetails
EASN215
KASN215
QASN215
WASN215

Catalytic Information from CSA
site_idMCSA1
Number of Residues
DetailsM-CSA 246
ChainResidueDetails

site_idMCSA2
Number of Residues
DetailsM-CSA 246
ChainResidueDetails

site_idMCSA3
Number of Residues
DetailsM-CSA 246
ChainResidueDetails

site_idMCSA4
Number of Residues
DetailsM-CSA 246
ChainResidueDetails

224931

PDB entries from 2024-09-11

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