7CFT
Cryo-EM strucutre of human acid-sensing ion channel 1a in complex with snake toxin Mambalgin1 at pH 8.0
Summary for 7CFT
Entry DOI | 10.2210/pdb7cft/pdb |
Related | 7CFS |
EMDB information | 30347 |
Descriptor | Acid-sensing ion channel 1, Mambalgin-1, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | asic, human, mambalgin1 toxin, cryo-em structure, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 185155.07 |
Authors | Sun, D.M.,Liu, S.L.,Li, S.Y.,Yang, F.,Tian, C.L. (deposition date: 2020-06-28, release date: 2020-10-21) |
Primary citation | Sun, D.,Liu, S.,Li, S.,Zhang, M.,Yang, F.,Wen, M.,Shi, P.,Wang, T.,Pan, M.,Chang, S.,Zhang, X.,Zhang, L.,Tian, C.,Liu, L. Structural insights into human acid-sensing ion channel 1a inhibition by snake toxin mambalgin1. Elife, 9:-, 2020 Cited by PubMed: 32915133DOI: 10.7554/eLife.57096 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.9 Å) |
Structure validation
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