6ZJ6

Structure of the GH99 endo-alpha-mannanase from Bacteroides xylanisolvens in complex with cyclohexylmethyl-Glc-1,3-isofagomine

This is a non-PDB format compatible entry.

Summary for 6ZJ6

• Entry DOI: 10.2210/pdb6zj6/pdb
• Related: 6ZDC 6ZDF 6ZDK 6ZDL 6ZFA 6ZFN 6ZFQ 6ZJ1 6ZJ5
• Descriptor: Glycosyl hydrolase family 71, 1,2-ETHANEDIOL, ACETATE ION, ... (7 entities in total)
• Functional Keywords: hydrolase, mannosidase, retaining
• Biological source: Bacteroides xylanisolvens XB1A
• Total number of polymer chains: 1
• Total formula weight: 44666.42

Authors

Thompson, A.J.,Sobala, L.F.,Fernandes, P.Z.,Hakki, Z.,Howe, J.D.,Hill, M.,Zitzmann, N.,Davies, S.,Stamataki, Z.,Butters, T.D.,Alonzi, D.S.,Williams, S.J.,Davies, G.J. (deposition date: 2020-06-27, release date: 2020-11-18, Last modification date: 2024-01-31)

• Primary citation: Sobala, L.F.,Fernandes, P.Z.,Hakki, Z.,Thompson, A.J.,Howe, J.D.,Hill, M.,Zitzmann, N.,Davies, S.,Stamataki, Z.,Butters, T.D.,Alonzi, D.S.,Williams, S.J.,Davies, G.J.; Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target.; Proc.Natl.Acad.Sci.USA, 117:29595-29601, 2020; PubMed: 33154157; DOI: 10.1073/pnas.2013620117

Experimental method

X-RAY DIFFRACTION (1.09 Å)