6Y23

DDR1 kinase autoinhibited by its juxtamembrane region

Summary for 6Y23

Entry DOI	10.2210/pdb6y23/pdb
Descriptor	Epithelial discoidin domain-containing receptor 1, SULFATE ION (3 entities in total)
Functional Keywords	kinase, collagen, cell signalling, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	3
Total formula weight	117905.61
Authors	Sammon, D.,Hohenester, E.,Leitinger, B. (deposition date: 2020-02-14, release date: 2020-09-02, Last modification date: 2024-01-24)
Primary citation	Sammon, D.,Hohenester, E.,Leitinger, B. Two-step release of kinase autoinhibition in discoidin domain receptor 1. Proc.Natl.Acad.Sci.USA, 117:22051-22060, 2020 Cited by PubMed: 32839343 DOI: 10.1073/pnas.2007271117 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.58 Å)

Structure validation