6Y23
DDR1 kinase autoinhibited by its juxtamembrane region
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Epithelial discoidin domain-containing receptor 1 | polymer | 350 | 39045.7 | 3 | UniProt (Q08345) Pfam (PF07714) In PDB | Homo sapiens (Human) | Epithelial discoidin domain receptor 1,CD167 antigen-like family member A,Cell adhesion kinase,Discoidin receptor tyrosine kinase,HGK2,Mammary carcinoma kinase 10,MCK-10,Protein-tyrosine kinase 3A,Protein-tyrosine kinase RTK-6,TRK E,Tyrosine kinase DDR,Tyrosine-protein kinase CAK |
| 2 | A, B, C | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
| 3 | water | water | 18.0 | 40 | Chemie (HOH) |
Sequence modifications
A, B, C: 566 - 913 (UniProt: Q08345)
| PDB | External Database | Details |
|---|---|---|
| Gly 564 | - | expression tag |
| Pro 565 | - | expression tag |
| Phe 569 | Tyr 569 | engineered mutation |
| Phe 586 | Tyr 586 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 117137.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 768.5 | |
| All* | Total formula weight | 117905.6 |
