6VKP

Crystal structure of DPO4 extension past 8-oxoadenine (oxoA) and dG

Summary for 6VKP

• Entry DOI: 10.2210/pdb6vkp/pdb
• Descriptor: DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*AP*GP*AP*TP*TP*CP*G)-3'), DNA (5'-D(*TP*TP*CP*AP*TP*(A38)P*GP*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*CP*C)-3'), DNA polymerase IV, ... (6 entities in total)
• Functional Keywords: dpo4, y-family dna polymerase, translesion synthesis, transferase, extension, transferase-dna complex, transferase/dna
• Biological source: Saccharolobus solfataricus; More
• Total number of polymer chains: 6
• Total formula weight: 99349.81

Authors

Jung, H.,Lee, S. (deposition date: 2020-01-21, release date: 2021-01-27, Last modification date: 2023-10-11)

• Primary citation: Jung, H.,Lee, S.; Insights into the mismatch discrimination mechanism of Y-family DNA polymerase Dpo4.; Biochem.J., 478:1769-1781, 2021; PubMed: 33881499; DOI: 10.1042/BCJ20210162

Experimental method

X-RAY DIFFRACTION (2.54 Å)