6VKP

Crystal structure of DPO4 extension past 8-oxoadenine (oxoA) and dG

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0003677	molecular_function	DNA binding
A	0003684	molecular_function	damaged DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0005737	cellular_component	cytoplasm
A	0006260	biological_process	DNA replication
A	0006261	biological_process	DNA-templated DNA replication
A	0006281	biological_process	DNA repair
A	0006974	biological_process	DNA damage response
A	0042276	biological_process	error-prone translesion synthesis
A	0046872	molecular_function	metal ion binding
D	0000287	molecular_function	magnesium ion binding
D	0003677	molecular_function	DNA binding
D	0003684	molecular_function	damaged DNA binding
D	0003887	molecular_function	DNA-directed DNA polymerase activity
D	0005737	cellular_component	cytoplasm
D	0006260	biological_process	DNA replication
D	0006261	biological_process	DNA-templated DNA replication
D	0006281	biological_process	DNA repair
D	0006974	biological_process	DNA damage response
D	0042276	biological_process	error-prone translesion synthesis
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue MG A 401

Chain	Residue
A	ASP7
A	SER103
A	ASP105
A	GLU106
A	DZ4403
A	HOH507
P	DG13
P	HOH103

---

site_id	AC2
Number of Residues	4
Details	binding site for residue MG A 402

Chain	Residue
A	PHE8
A	ASP105
A	DZ4403
A	ASP7

---

site_id	AC3
Number of Residues	23
Details	binding site for residue DZ4 A 403

Chain	Residue
A	ASP7
A	PHE8
A	ASP9
A	TYR10
A	PHE11
A	TYR12
A	ALA44
A	THR45
A	TYR48
A	ARG51
A	ASP105
A	LYS159
A	MG401
A	MG402
A	HOH507
A	HOH510
A	HOH512
A	HOH514
P	DG13
P	HOH101
P	HOH105
T	DT5
T	A386

---

site_id	AC4
Number of Residues	7
Details	binding site for residue MG D 401

Chain	Residue
B	DG13
B	HOH105
D	ASP7
D	ASP105
D	GLU106
D	DZ4403
D	HOH505

---

site_id	AC5
Number of Residues	4
Details	binding site for residue MG D 402

Chain	Residue
D	ASP7
D	PHE8
D	ASP105
D	DZ4403

---

site_id	AC6
Number of Residues	22
Details	binding site for residue DZ4 D 403

Chain	Residue
B	DG13
B	HOH102
B	HOH105
C	DT5
C	A386
D	ASP7
D	PHE8
D	ASP9
D	TYR10
D	PHE11
D	TYR12
D	ALA44
D	THR45
D	TYR48
D	ARG51
D	ASP105
D	LYS159
D	MG401
D	MG402
D	HOH504
D	HOH507
D	HOH511

---

site_id	AC7
Number of Residues	9
Details	binding site for Di-nucleotide DT C 5 and A38 C 6

Chain	Residue
C	DA4
C	DG7
D	VAL32
D	ALA42
D	ILE248
D	THR250
D	ARG331
D	ARG332
D	DZ4403

---

site_id	AC8
Number of Residues	9
Details	binding site for Di-nucleotide A38 C 6 and DG C 7

Chain	Residue
B	DC12
C	DT5
C	DA8
D	ARG247
D	ILE248
D	THR250
D	ARG332
D	ARG336
D	DZ4403

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE:

Chain	Residue	Details
A	GLU106
D	GLU106

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING:

Chain	Residue	Details
A	ASP7
A	ASP105
D	ASP7
D	ASP105

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	SITE: Substrate discrimination

Chain	Residue	Details
A	TYR12
D	TYR12

---