6VAX

Crystal structure of human SDHA-SDHAF2 assembly intermediate

Summary for 6VAX

Entry DOI	10.2210/pdb6vax/pdb
Descriptor	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, Succinate dehydrogenase assembly factor 2, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ... (9 entities in total)
Functional Keywords	sdha, flavoprotein, sdhaf2, assembly intermediate, respiratory complex, oxidoreductase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	180841.97
Authors	Sharma, P.,Maklashina, E.,Cecchini, G.,Iverson, T.M. (deposition date: 2019-12-18, release date: 2020-08-26, Last modification date: 2023-10-25)
Primary citation	Sharma, P.,Maklashina, E.,Cecchini, G.,Iverson, T.M. The roles of SDHAF2 and dicarboxylate in covalent flavinylation of SDHA, the human complex II flavoprotein. Proc.Natl.Acad.Sci.USA, 117:23548-23556, 2020 Cited by PubMed: 32887801 DOI: 10.1073/pnas.2007391117 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.59 Å)

Structure validation