6VAX
Crystal structure of human SDHA-SDHAF2 assembly intermediate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | polymer | 632 | 69416.4 | 2 | UniProt (P31040) Pfam (PF00890) Pfam (PF02910) | Homo sapiens (Human) | Flavoprotein subunit of complex II,Fp |
| 2 | B, D (B, D) | Succinate dehydrogenase assembly factor 2, mitochondrial | polymer | 166 | 19626.4 | 2 | UniProt (Q9NX18) Pfam (PF03937) | Homo sapiens (Human) | SDHAF2 |
| 3 | E, O (A, C) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 2 | Chemie (FAD) | |||
| 4 | F, P (A, C) | OXALOACETATE ION | non-polymer | 131.1 | 2 | Chemie (OAA) | |||
| 5 | G (A) | MALONATE ION | non-polymer | 102.0 | 1 | Chemie (MLI) | |||
| 6 | H, N (A, C) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | I, Q (A, C) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 8 | J, K, L, M, R... (A, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 9 | Chemie (EDO) | |||
| 9 | W, X, Y, Z (A, B, C, D) | water | water | 18.0 | 99 | Chemie (HOH) |
Sequence modifications
A, C: 44 - 664 (UniProt: P31040)
| PDB | External Database | Details |
|---|---|---|
| Met 33 | - | expression tag |
| Arg 34 | - | expression tag |
| Gly 35 | - | expression tag |
| Ser 36 | - | expression tag |
| His 37 | - | expression tag |
| His 38 | - | expression tag |
| His 39 | - | expression tag |
| His 40 | - | expression tag |
| His 41 | - | expression tag |
| His 42 | - | expression tag |
| Gly 43 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 178085.7 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 2756.3 | |
| All* | Total formula weight | 180842.0 |
