6V2H

Crystal structure of CDYL2 in complex with H3tK27me3

Summary for 6V2H

• Entry DOI: 10.2210/pdb6v2h/pdb
• Related: 6V2D
• Descriptor: Chromodomain Y-like protein 2, H3tK27me3, NICKEL (II) ION, ... (4 entities in total)
• Functional Keywords: histone, chromodomain, structural genomics, structural genomics consortium, sgc, gene regulation
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 12
• Total formula weight: 52677.35

Authors

Dong, C.,Tempel, W.,Walker, J.R.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2019-11-22, release date: 2019-12-25, Last modification date: 2023-10-11)

• Primary citation: Dong, C.,Liu, Y.,Lyu, T.J.,Beldar, S.,Lamb, K.N.,Tempel, W.,Li, Y.,Li, Z.,James, L.I.,Qin, S.,Wang, Y.,Min, J.; Structural Basis for the Binding Selectivity of Human CDY Chromodomains.; Cell Chem Biol, 27:827-838.e7, 2020; PubMed: 32470319; DOI: 10.1016/j.chembiol.2020.05.007

Experimental method

X-RAY DIFFRACTION (2.6 Å)