6ULA

Crystal structure of human GAC in complex with inhibitor UPGL00012

Summary for 6ULA

• Entry DOI: 10.2210/pdb6ula/pdb
• Descriptor: Glutaminase kidney isoform, mitochondrial, 2-cyclopropyl-N-{5-[4-({5-[(cyclopropylacetyl)amino]-1,3,4-thiadiazol-2-yl}oxy)piperidin-1-yl]-1,3,4-thiadiazol-2-yl}acetamide (2 entities in total)
• Functional Keywords: inhibitor, complex, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 8
• Total formula weight: 466046.28

Authors

Huang, Q.,Cerione, R.A. (deposition date: 2019-10-07, release date: 2020-10-14, Last modification date: 2023-10-11)

• Primary citation: Huang, Q.,Cerione, R.A.; Crystal structure of human GAC in complex with inhibitor UPGL00030; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.95 Å)