6ULA

Crystal structure of human GAC in complex with inhibitor UPGL00012

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Glutaminase kidney isoform, mitochondrial	polymer	527	58024.0	8	UniProt (O94925) Pfam (PF17959) Pfam (PF04960) In PDB	Homo sapiens (Human)	GLS,K-glutaminase,L-glutamine amidohydrolase
2	A, C, E	2-cyclopropyl-N-{5-[4-({5-[(cyclopropylacetyl)amino]-1,3,4-thiadiazol-2-yl}oxy)piperidin-1-yl]-1,3,4-thiadiazol-2-yl}acetamide	non-polymer		463.6	4	Chemie (QA4)

Sequence modifications

A, B, C, D, E, G, F, H: 72 - 598 (UniProt: O94925)

PDB	External Database	Details
Ala 268	Val 268	conflict

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	464192.0
Non-Polymers*	Number of molecules	4
	Total formula weight	1854.3
All*	Total formula weight	466046.3

*Water molecules are not included.