6ULA
Crystal structure of human GAC in complex with inhibitor UPGL00012
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Glutaminase kidney isoform, mitochondrial | polymer | 527 | 58024.0 | 8 | UniProt (O94925) Pfam (PF17959) Pfam (PF04960) In PDB | Homo sapiens (Human) | GLS,K-glutaminase,L-glutamine amidohydrolase |
2 | A, C, E | 2-cyclopropyl-N-{5-[4-({5-[(cyclopropylacetyl)amino]-1,3,4-thiadiazol-2-yl}oxy)piperidin-1-yl]-1,3,4-thiadiazol-2-yl}acetamide | non-polymer | 463.6 | 4 | Chemie (QA4) |
Sequence modifications
A, B, C, D, E, G, F, H: 72 - 598 (UniProt: O94925)
PDB | External Database | Details |
---|---|---|
Ala 268 | Val 268 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 464192.0 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1854.3 | |
All* | Total formula weight | 466046.3 |