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6UJA

Integrin alpha-v beta-8 in complex with pro-TGF-beta1

Summary for 6UJA
Entry DOI10.2210/pdb6uja/pdb
EMDB information20794 20795 20796 20797 20798 20799 20800 20801 20802 21125
DescriptorIntegrin alpha-V, Integrin beta-8, Transforming growth factor beta-1 proprotein, ... (8 entities in total)
Functional Keywordsglycoprotein, adhesion, signaling, signaling protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains3
Total formula weight239183.35
Authors
Campbell, M.G.,Cormier, A.,Cheng, Y.,Nishimura, S.L. (deposition date: 2019-10-02, release date: 2020-02-05, Last modification date: 2020-07-29)
Primary citationCampbell, M.G.,Cormier, A.,Ito, S.,Seed, R.I.,Bondesson, A.J.,Lou, J.,Marks, J.D.,Baron, J.L.,Cheng, Y.,Nishimura, S.L.
Cryo-EM Reveals Integrin-Mediated TGF-beta Activation without Release from Latent TGF-beta.
Cell, 180:490-, 2020
Cited by
PubMed: 31955848
DOI: 10.1016/j.cell.2019.12.030
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.3 Å)
Structure validation

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