6UJA
Integrin alpha-v beta-8 in complex with pro-TGF-beta1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Integrin alpha-V | polymer | 1018 | 112813.4 | 1 | UniProt (P06756) Pfam (PF01839) Pfam (PF08441) Pfam (PF20805) Pfam (PF20806) Pfam (PF00357) | Homo sapiens (Human) | Vitronectin receptor,Vitronectin receptor subunit alpha |
| 2 | B (B) | Integrin beta-8 | polymer | 727 | 81276.7 | 1 | UniProt (P26012) Pfam (PF07974) Pfam (PF17205) Pfam (PF00362) | Homo sapiens (Human) | |
| 3 | C (D) | Transforming growth factor beta-1 proprotein | polymer | 363 | 41434.4 | 1 | UniProt (P07200) Pfam (PF00688) Pfam (PF00019) | Sus scrofa (Pig) | |
| 4 | D (C) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G56014GC) | |||
| 5 | E, F, G, H (E, F, G, H) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
| 6 | I, J, K, L, N (A, B) | CALCIUM ION | non-polymer | 40.1 | 5 | Chemie (CA) | |||
| 7 | M, P, Q (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 8 | O (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence modifications
D: 1 - 361 (UniProt: P07200)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 235524.5 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 2770.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 888.3 | |
| All* | Total formula weight | 239183.4 |
