6TM3
Structure of methylene-tetrahydromethanopterin dehydrogenase from Methylorubrum extorquens AM1 in a close conformation containing NADP+ and methylene-H4MPT
Summary for 6TM3
Entry DOI | 10.2210/pdb6tm3/pdb |
Descriptor | Bifunctional protein MdtA, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GLYCEROL, ... (7 entities in total) |
Functional Keywords | one-carbon metabolism; enzyme catalysis; dehydrogenase; conformational changes; methylotrophy, oxidoreductase |
Biological source | Methylorubrum extorquens AM1 |
Total number of polymer chains | 1 |
Total formula weight | 34019.76 |
Authors | Wagner, T.,Huang, G.,Demmer, U.,Warkentin, E.,Ermler, U.,Shima, S. (deposition date: 2019-12-03, release date: 2020-02-26, Last modification date: 2024-01-24) |
Primary citation | Huang, G.,Wagner, T.,Demmer, U.,Warkentin, E.,Ermler, U.,Shima, S. The Hydride Transfer Process in NADP-dependent Methylene-tetrahydromethanopterin Dehydrogenase. J.Mol.Biol., 432:2042-2054, 2020 Cited by PubMed: 32061937DOI: 10.1016/j.jmb.2020.01.042 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.08 Å) |
Structure validation
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