6TM3

Structure of methylene-tetrahydromethanopterin dehydrogenase from Methylorubrum extorquens AM1 in a close conformation containing NADP+ and methylene-H4MPT

Summary for 6TM3

Entry DOI	10.2210/pdb6tm3/pdb
Descriptor	Bifunctional protein MdtA, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, GLYCEROL, ... (7 entities in total)
Functional Keywords	one-carbon metabolism; enzyme catalysis; dehydrogenase; conformational changes; methylotrophy, oxidoreductase
Biological source	Methylorubrum extorquens AM1
Total number of polymer chains	1
Total formula weight	34019.76
Authors	Wagner, T.,Huang, G.,Demmer, U.,Warkentin, E.,Ermler, U.,Shima, S. (deposition date: 2019-12-03, release date: 2020-02-26, Last modification date: 2024-01-24)
Primary citation	Huang, G.,Wagner, T.,Demmer, U.,Warkentin, E.,Ermler, U.,Shima, S. The Hydride Transfer Process in NADP-dependent Methylene-tetrahydromethanopterin Dehydrogenase. J.Mol.Biol., 432:2042-2054, 2020 Cited by PubMed: 32061937 DOI: 10.1016/j.jmb.2020.01.042 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.08 Å)

Structure validation