6TM3

Structure of methylene-tetrahydromethanopterin dehydrogenase from Methylorubrum extorquens AM1 in a close conformation containing NADP+ and methylene-H4MPT

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Bifunctional protein MdtA	polymer	303	31512.7	1	UniProt (P55818) Pfam (PF09176) In PDB	Methylorubrum extorquens AM1
2	A	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	1	Chemie (NAP)
3	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	A	5,10-DIMETHYLENE TETRAHYDROMETHANOPTERIN	non-polymer		788.7	1	Chemie (H4M)
5	A	1,2-ETHANEDIOL	non-polymer		62.1	14	Chemie (EDO)
6	A	LITHIUM ION	non-polymer		6.9	2	Chemie (LI)
7		water	water		18.0	501	Chemie (HOH)

Sequence modifications

A: 1 - 288 (UniProt: P55818)

PDB	External Database	Details
Val 289	-	expression tag
Asp 290	-	expression tag
Lys 291	-	expression tag
Leu 292	-	expression tag
Ala 293	-	expression tag
Ala 294	-	expression tag
Ala 295	-	expression tag
Leu 296	-	expression tag
Glu 297	-	expression tag
His 298	-	expression tag
His 299	-	expression tag
His 300	-	expression tag
His 301	-	expression tag
His 302	-	expression tag
His 303	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	31512.7
Non-Polymers*	Number of molecules	19
	Total formula weight	2507.0
All*	Total formula weight	34019.8

*Water molecules are not included.