NAD+-dependent fungal formate dehydrogenase from Chaetomium thermophilum: A ternary complex with the oxidised form of the cofactor NAD+ and the substrate formate both at a primary and secondary sites.

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Summary for 6T8Z

DescriptorFormate dehydrogenase, DI(HYDROXYETHYL)ETHER, FORMIC ACID, ... (6 entities in total)
Functional Keywordsnad+ dependent formate dehydrogenase, cytosolic protein
Biological sourceChaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)
Total number of polymer chains4
Total molecular weight186764.81
Isupov, M.N.,Yelmazer, B.,De Rose, S.A.,Littlechild, J.A. (deposition date: 2019-10-25, release date: 2020-11-18)
Primary citation
Yelmazer, B.,Isupov, M.N.,De Rose, S.A.,Bulut, H.,Benninghoff, J.C.,Binay, B.,Littlechild, J.A.
Structural insights into the reduced cofactor structure and the formate ternary complex of the fungal NAD+-dependent formate dehydrogenase from Chaetomium thermophilum
To Be Published,
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.21860 0.5% 3.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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PDB entries from 2020-11-25