6T8Z
NAD+-dependent fungal formate dehydrogenase from Chaetomium thermophilum: A ternary complex with the oxidised form of the cofactor NAD+ and the substrate formate both at a primary and secondary sites.
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (AAA, BBB, CCC, DDD) | Formate dehydrogenase | polymer | 410 | 45641.4 | 4 | UniProt (G0SGU4) Pfam (PF00389) Pfam (PF02826) | Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) | FDH,NAD-dependent formate dehydrogenase |
| 2 | AA, E, F, O, T... (DDD, AAA, BBB, CCC) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 7 | Chemie (PEG) | |||
| 3 | BA, CA, G, H, P... (DDD, AAA, BBB, CCC) | FORMIC ACID | non-polymer | 46.0 | 8 | Chemie (FMT) | |||
| 4 | DA, I, R, X (DDD, AAA, BBB, CCC) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 5 | J, K, L, M, N... (AAA, BBB, CCC) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 6 | EA, FA, GA, HA (AAA, BBB, CCC, DDD) | water | water | 18.0 | 1965 | Chemie (HOH) |
Sequence modifications
AAA, BBB, CCC, DDD: 1 - 370 (UniProt: G0SGU4)
| PDB | External Database | Details |
|---|---|---|
| Met -33 | - | initiating methionine |
| Ala -32 | - | expression tag |
| His -31 | - | expression tag |
| His -30 | - | expression tag |
| His -29 | - | expression tag |
| His -28 | - | expression tag |
| His -27 | - | expression tag |
| His -26 | - | expression tag |
| Val -25 | - | expression tag |
| Gly -24 | - | expression tag |
| Thr -23 | - | expression tag |
| Gly -22 | - | expression tag |
| Ser -21 | - | expression tag |
| Asn -20 | - | expression tag |
| Asp -19 | - | expression tag |
| Asp -18 | - | expression tag |
| Asp -17 | - | expression tag |
| Asp -16 | - | expression tag |
| Lys -15 | - | expression tag |
| Ser -14 | - | expression tag |
| Pro -13 | - | expression tag |
| Asp -12 | - | expression tag |
| Pro -11 | - | expression tag |
| Asn -10 | - | expression tag |
| Trp -9 | - | expression tag |
| Glu -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Val -6 | - | expression tag |
| Tyr -5 | - | expression tag |
| Thr -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Arg -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Gln 0 | - | expression tag |
| His 371 | - | expression tag |
| His 372 | - | expression tag |
| His 373 | - | expression tag |
| His 374 | - | expression tag |
| His 375 | - | expression tag |
| His 376 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 182565.6 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 4199.2 | |
| All* | Total formula weight | 186764.8 |
