6P08

Ternary structure of the E52D mutant of ANT-4'' with Neomycin, AMP and Pyrophosphate

Summary for 6P08

• Entry DOI: 10.2210/pdb6p08/pdb
• Descriptor: Kanamycin nucleotidyltransferase, NEOMYCIN, PYROPHOSPHATE, ... (6 entities in total)
• Functional Keywords: aminoglycoside nucelotidyl transferase (ant), aminoglycoside modifying enzymes (agmes), dna polymerase, antibiotic, transferase-antibiotic complex, transferase/antibiotic
• Biological source: Bacillus sp.
• Total number of polymer chains: 2
• Total formula weight: 60620.61

Authors

Selvaraj, B.,Cuneo, M.J. (deposition date: 2019-05-16, release date: 2020-01-29, Last modification date: 2023-10-11)

• Primary citation: Selvaraj, B.,Kocaman, S.,Trifas, M.,Serpersu, E.H.,Cuneo, M.J.; "Catch and Release": a Variation of the Archetypal Nucleotidyl Transfer Reaction; Acs Catalysis, 10:3548-3555, 2020; DOI: 10.1021/acscatal.9b05201

Experimental method

X-RAY DIFFRACTION (2.27 Å)