6P08
Ternary structure of the E52D mutant of ANT-4'' with Neomycin, AMP and Pyrophosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, D) | Kanamycin nucleotidyltransferase | polymer | 256 | 29121.9 | 2 | UniProt (P05058) Pfam (PF07827) UniProt (by SIFTS) (P05057) | Bacillus sp. | |
| 2 | C, I (A) | NEOMYCIN | non-polymer | 614.6 | 2 | Chemie (NMY) | |||
| 3 | D, K (A, D) | PYROPHOSPHATE | non-polymer | 178.0 | 2 | Chemie (PPV) | |||
| 4 | E, F, J, L (A, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 5 | G, H (A) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 2 | Chemie (AMP) | |||
| 6 | M, N (A, D) | water | water | 18.0 | 228 | Chemie (HOH) |
Sequence modifications
A, D: 1 - 253 (UniProt: P05058)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Asp 52 | Glu 52 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58243.7 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2376.9 | |
| All* | Total formula weight | 60620.6 |
