6O1H

Tryptophan synthase Q114A mutant in complex with N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site, cesium ion at the metal coordination site, and 2-aminophenol quinonoid at the enzyme beta site

6O1H の概要

• エントリーDOI: 10.2210/pdb6o1h/pdb
• 関連するPDBエントリー: 4HN4 4HPJ 4HPX 4HT3 4KKX 4XUG 5CGQ 6C73
• 分子名称: Tryptophan synthase alpha chain, Tryptophan synthase beta chain, DIMETHYL SULFOXIDE, ... (9 entities in total)
• 機能のキーワード: tryptophan synthase, mutant q114a, lyase-inhibitor, protein complex, salmonella, lyase
• 由来する生物種: Salmonella typhimurium (Salmonella enterica subsp. enterica serovar Typhimurium); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 73791.97

構造登録者

Hilario, E.,Dunn, M.F.,Mueller, L.J.,Fan, L. (登録日: 2019-02-19, 公開日: 2020-02-19, 最終更新日: 2023-10-11)

• 主引用文献: Hilario, E.,Dunn, M.F.,Mueller, L.J.,Fan, L.; Crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-Q114A with 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate (F9F) at the alpha-site, Cesium ion at the metal coordination site, and [3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-ylmethyl]-serine (PLS) at the beta-site.; To be Published,

実験手法

X-RAY DIFFRACTION (1.64 Å)