5CGQ
Crystal structure of Tryptophan Synthase from Salmonella typhimurium in complex with F9 ligand in the alpha-site and the product L-Tryptophan in the beta-site.
Summary for 5CGQ
Entry DOI | 10.2210/pdb5cgq/pdb |
Related | 2CLI 2CLL 3PR2 4HN4 4HPJ 4HPX 4HT3 4XUG 4Y6G 4ZQC 5BW6 |
Descriptor | Tryptophan synthase alpha chain, Tryptophan synthase beta chain, 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, ... (9 entities in total) |
Functional Keywords | lyase, carbon-oxygen lyase, tryptophan biosynthesis, salmonella typhimurium, f6f, inhibitor, allosteric enzyme, aromatic amino acid biosynthesis, pyridoxal phosphate, transferase, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Salmonella enterica subsp. enterica serovar Typhimurium More |
Total number of polymer chains | 2 |
Total formula weight | 73058.22 |
Authors | Hilario, E.,Caulkins, B.G.,Young, R.P.,Dunn, M.F.,Mueller, L.J.,Fan, L. (deposition date: 2015-07-09, release date: 2016-07-13, Last modification date: 2023-09-27) |
Primary citation | Hilario, E.,Caulkins, B.G.,Young, R.P.,Dunn, M.F.,Mueller, L.J.,Fan, L. Crystal structure of Tryptophan Synthase from Salmonella typhimurium in complex with F9 ligand and the product L-Tryptophan in the beta-site. To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.18 Å) |
Structure validation
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