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5CGQ

Crystal structure of Tryptophan Synthase from Salmonella typhimurium in complex with F9 ligand in the alpha-site and the product L-Tryptophan in the beta-site.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tryptophan synthase alpha chainpolymer26828698.81UniProt (P00929)
Pfam (PF00290)
Salmonella enterica subsp. enterica serovar Typhimurium
2B
(B)
Tryptophan synthase beta chainpolymer39742918.91UniProt (P0A2K1)
Pfam (PF00291)
Salmonella enterica subsp. enterica serovar Typhimurium
3C
(A)
2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATEnon-polymer365.21Chemie (F9F)
4D, H, I
(A, B)
CESIUM IONnon-polymer132.93Chemie (CS)
5E
(B)
PYRIDOXAL-5'-PHOSPHATEnon-polymer247.11Chemie (PLP)
6F
(B)
TRYPTOPHANnon-polymer204.21Chemie (TRP)
7G
(B)
BICINEnon-polymer163.21Chemie (BCN)
8J
(B)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
9K, L
(A, B)
waterwater18.0787Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight71617.7
Non-Polymers*Number of molecules8
Total formula weight1440.5
All*Total formula weight73058.2
*Water molecules are not included.

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PDB entries from 2026-02-11

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