6LI0
Crystal structure of GPR52 in complex with agonist c17
Summary for 6LI0
Entry DOI | 10.2210/pdb6li0/pdb |
Descriptor | Chimera of G-protein coupled receptor 52 and Flavodoxin, N-(2-hydroxyethyl)-5-(hydroxymethyl)-3-methyl-1-[2-[[3-(trifluoromethyl)phenyl]methyl]-1-benzothiophen-7-yl]pyrazole-4-carboxamide, FLAVIN MONONUCLEOTIDE, ... (7 entities in total) |
Functional Keywords | human gpr52 receptor, class a, orphan gpcr, membrane protein, agonist c17, flavodoxin, lcp |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 1 |
Total formula weight | 60648.52 |
Authors | |
Primary citation | Lin, X.,Li, M.,Wang, N.,Wu, Y.,Luo, Z.,Guo, S.,Han, G.W.,Li, S.,Yue, Y.,Wei, X.,Xie, X.,Chen, Y.,Zhao, S.,Wu, J.,Lei, M.,Xu, F. Structural basis of ligand recognition and self-activation of orphan GPR52. Nature, 579:152-157, 2020 Cited by PubMed: 32076264DOI: 10.1038/s41586-020-2019-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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