6HGO

Crystal Structure of human IL-17F

Summary for 6HGO

• Entry DOI: 10.2210/pdb6hgo/pdb
• Related: 6HG4 6HG9 6HGA
• Descriptor: Interleukin-17F, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: cystine-knot, cytokine, immune system
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 63967.67

Authors

Rondeau, J.M.,Goepfert, A. (deposition date: 2018-08-23, release date: 2019-11-20, Last modification date: 2024-01-17)

• Primary citation: Goepfert, A.,Lehmann, S.,Blank, J.,Kolbinger, F.,Rondeau, J.M.; Structural Analysis Reveals that the Cytokine IL-17F Forms a Homodimeric Complex with Receptor IL-17RC to Drive IL-17RA-Independent Signaling.; Immunity, 52:499-512.e5, 2020; PubMed: 32187518; DOI: 10.1016/j.immuni.2020.02.004

Experimental method

X-RAY DIFFRACTION (2.1 Å)