6HGO

Crystal Structure of human IL-17F

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001819	biological_process	positive regulation of cytokine production
A	0002225	biological_process	positive regulation of antimicrobial peptide production
A	0002250	biological_process	adaptive immune response
A	0002376	biological_process	immune system process
A	0005125	molecular_function	cytokine activity
A	0005126	molecular_function	cytokine receptor binding
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005886	cellular_component	plasma membrane
A	0006954	biological_process	inflammatory response
A	0016525	biological_process	negative regulation of angiogenesis
A	0017015	biological_process	regulation of transforming growth factor beta receptor signaling pathway
A	0019955	molecular_function	cytokine binding
A	0032645	biological_process	regulation of granulocyte macrophage colony-stimulating factor production
A	0032663	biological_process	regulation of interleukin-2 production
A	0032675	biological_process	regulation of interleukin-6 production
A	0032677	biological_process	regulation of interleukin-8 production
A	0032755	biological_process	positive regulation of interleukin-6 production
A	0032761	biological_process	positive regulation of lymphotoxin A production
A	0042803	molecular_function	protein homodimerization activity
A	0045087	biological_process	innate immune response
A	0046982	molecular_function	protein heterodimerization activity
A	0050829	biological_process	defense response to Gram-negative bacterium
A	0050830	biological_process	defense response to Gram-positive bacterium
A	0051216	biological_process	cartilage development
A	0070534	biological_process	protein K63-linked ubiquitination
A	0072538	biological_process	T-helper 17 type immune response
A	0080090	biological_process	regulation of primary metabolic process
A	0097400	biological_process	interleukin-17-mediated signaling pathway
A	1903557	biological_process	positive regulation of tumor necrosis factor superfamily cytokine production
A	2000340	biological_process	positive regulation of chemokine (C-X-C motif) ligand 1 production
B	0001819	biological_process	positive regulation of cytokine production
B	0002225	biological_process	positive regulation of antimicrobial peptide production
B	0002250	biological_process	adaptive immune response
B	0002376	biological_process	immune system process
B	0005125	molecular_function	cytokine activity
B	0005126	molecular_function	cytokine receptor binding
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0005886	cellular_component	plasma membrane
B	0006954	biological_process	inflammatory response
B	0016525	biological_process	negative regulation of angiogenesis
B	0017015	biological_process	regulation of transforming growth factor beta receptor signaling pathway
B	0019955	molecular_function	cytokine binding
B	0032645	biological_process	regulation of granulocyte macrophage colony-stimulating factor production
B	0032663	biological_process	regulation of interleukin-2 production
B	0032675	biological_process	regulation of interleukin-6 production
B	0032677	biological_process	regulation of interleukin-8 production
B	0032755	biological_process	positive regulation of interleukin-6 production
B	0032761	biological_process	positive regulation of lymphotoxin A production
B	0042803	molecular_function	protein homodimerization activity
B	0045087	biological_process	innate immune response
B	0046982	molecular_function	protein heterodimerization activity
B	0050829	biological_process	defense response to Gram-negative bacterium
B	0050830	biological_process	defense response to Gram-positive bacterium
B	0051216	biological_process	cartilage development
B	0070534	biological_process	protein K63-linked ubiquitination
B	0072538	biological_process	T-helper 17 type immune response
B	0080090	biological_process	regulation of primary metabolic process
B	0097400	biological_process	interleukin-17-mediated signaling pathway
B	1903557	biological_process	positive regulation of tumor necrosis factor superfamily cytokine production
B	2000340	biological_process	positive regulation of chemokine (C-X-C motif) ligand 1 production
C	0001819	biological_process	positive regulation of cytokine production
C	0002225	biological_process	positive regulation of antimicrobial peptide production
C	0002250	biological_process	adaptive immune response
C	0002376	biological_process	immune system process
C	0005125	molecular_function	cytokine activity
C	0005126	molecular_function	cytokine receptor binding
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0005886	cellular_component	plasma membrane
C	0006954	biological_process	inflammatory response
C	0016525	biological_process	negative regulation of angiogenesis
C	0017015	biological_process	regulation of transforming growth factor beta receptor signaling pathway
C	0019955	molecular_function	cytokine binding
C	0032645	biological_process	regulation of granulocyte macrophage colony-stimulating factor production
C	0032663	biological_process	regulation of interleukin-2 production
C	0032675	biological_process	regulation of interleukin-6 production
C	0032677	biological_process	regulation of interleukin-8 production
C	0032755	biological_process	positive regulation of interleukin-6 production
C	0032761	biological_process	positive regulation of lymphotoxin A production
C	0042803	molecular_function	protein homodimerization activity
C	0045087	biological_process	innate immune response
C	0046982	molecular_function	protein heterodimerization activity
C	0050829	biological_process	defense response to Gram-negative bacterium
C	0050830	biological_process	defense response to Gram-positive bacterium
C	0051216	biological_process	cartilage development
C	0070534	biological_process	protein K63-linked ubiquitination
C	0072538	biological_process	T-helper 17 type immune response
C	0080090	biological_process	regulation of primary metabolic process
C	0097400	biological_process	interleukin-17-mediated signaling pathway
C	1903557	biological_process	positive regulation of tumor necrosis factor superfamily cytokine production
C	2000340	biological_process	positive regulation of chemokine (C-X-C motif) ligand 1 production
D	0001819	biological_process	positive regulation of cytokine production
D	0002225	biological_process	positive regulation of antimicrobial peptide production
D	0002250	biological_process	adaptive immune response
D	0002376	biological_process	immune system process
D	0005125	molecular_function	cytokine activity
D	0005126	molecular_function	cytokine receptor binding
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0005615	cellular_component	extracellular space
D	0005886	cellular_component	plasma membrane
D	0006954	biological_process	inflammatory response
D	0016525	biological_process	negative regulation of angiogenesis
D	0017015	biological_process	regulation of transforming growth factor beta receptor signaling pathway
D	0019955	molecular_function	cytokine binding
D	0032645	biological_process	regulation of granulocyte macrophage colony-stimulating factor production
D	0032663	biological_process	regulation of interleukin-2 production
D	0032675	biological_process	regulation of interleukin-6 production
D	0032677	biological_process	regulation of interleukin-8 production
D	0032755	biological_process	positive regulation of interleukin-6 production
D	0032761	biological_process	positive regulation of lymphotoxin A production
D	0042803	molecular_function	protein homodimerization activity
D	0045087	biological_process	innate immune response
D	0046982	molecular_function	protein heterodimerization activity
D	0050829	biological_process	defense response to Gram-negative bacterium
D	0050830	biological_process	defense response to Gram-positive bacterium
D	0051216	biological_process	cartilage development
D	0070534	biological_process	protein K63-linked ubiquitination
D	0072538	biological_process	T-helper 17 type immune response
D	0080090	biological_process	regulation of primary metabolic process
D	0097400	biological_process	interleukin-17-mediated signaling pathway
D	1903557	biological_process	positive regulation of tumor necrosis factor superfamily cytokine production
D	2000340	biological_process	positive regulation of chemokine (C-X-C motif) ligand 1 production

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19838198","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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