6GY2

Crystal structure of human Plk1-PBD in complex with WSSSLATPPTLSSpTVLI phosphopeptide from BRCA2

Summary for 6GY2

DescriptorSerine/threonine-protein kinase PLK1, Phosphopeptide of BRCA2, GLYCEROL, ... (4 entities in total)
Functional Keywordsphosphorylation, chromosomes alignement, dna repair, cell cycle
Biological sourceHomo sapiens (Human)
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Total number of polymer chains4
Total molecular weight60158.24
Authors
Miron, S.,Ropars, V.,Zinn-Justin, S. (deposition date: 2018-06-28, release date: 2019-07-10)
Primary citation
Ehlen, A.,Miron, S.,Martin, C.,Julien, M.,Theillet, F.X.,Boucherit, V.,Ropars, V.,Duchambon, P.,El Marjou, A.,Zinn-Justin, S.,Carreira, A.
Proper chromosome alignment depends on BRCA2 phosphorylation by PLK1
To Be Published,
Experimental method
X-RAY DIFFRACTION (3.11 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.22620 4.2% 0.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution