6GEK

TEAD4 (216-434);Y429F COMPLEXED WITH YAP PEPTIDE (60-100) AND MYRISTOATE (COVALENTLY BOUND) AT 2.28A (P212121 CRYSTAL FORM); MYRISTOYLATION WAS DONE BY ADDING MYR-COA

6GEK の概要

• エントリーDOI: 10.2210/pdb6gek/pdb
• 関連するPDBエントリー: 6GE3 6GE4 6GE5 6GE6 6GEC 6GEE 6GEG 6GEI
• 分子名称: Transcriptional enhancer factor TEF-3, Transcriptional coactivator YAP1, MYRISTIC ACID, ... (4 entities in total)
• 機能のキーワード: transcription, co-activator complex, protein-protein interaction
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 60726.80

構造登録者

Kallen, J. (登録日: 2018-04-26, 公開日: 2018-09-19, 最終更新日: 2024-01-17)

• 主引用文献: Mesrouze, Y.,Bokhovchuk, F.,Izaac, A.,Meyerhofer, M.,Zimmermann, C.,Fontana, P.,Schmelzle, T.,Erdmann, D.,Furet, P.,Kallen, J.,Chene, P.; Adaptation of the bound intrinsically disordered protein YAP to mutations at the YAP:TEAD interface.; Protein Sci., 27:1810-1820, 2018; PubMed: 30058229; DOI: 10.1002/pro.3493

実験手法

X-RAY DIFFRACTION (2.28 Å)