6GEK
TEAD4 (216-434);Y429F COMPLEXED WITH YAP PEPTIDE (60-100) AND MYRISTOATE (COVALENTLY BOUND) AT 2.28A (P212121 CRYSTAL FORM); MYRISTOYLATION WAS DONE BY ADDING MYR-COA
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue MYR A 501 |
| Chain | Residue |
| A | VAL316 |
| A | VAL334 |
| A | LYS344 |
| A | CYS367 |
| A | PHE415 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for Di-peptide MYR B 501 and CYS B 367 |
| Chain | Residue |
| B | TYR369 |
| B | MET370 |
| B | ILE371 |
| B | LYS344 |
| B | PRO365 |
| B | LEU366 |
| B | GLU368 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine; by LATS1 and LATS2","evidences":[{"source":"PubMed","id":"17974916","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18158288","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-lactoyllysine","evidences":[{"source":"PubMed","id":"38512451","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
