6GEK
TEAD4 (216-434);Y429F COMPLEXED WITH YAP PEPTIDE (60-100) AND MYRISTOATE (COVALENTLY BOUND) AT 2.28A (P212121 CRYSTAL FORM); MYRISTOYLATION WAS DONE BY ADDING MYR-COA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Transcriptional enhancer factor TEF-3 | polymer | 219 | 25484.7 | 2 | UniProt (Q15561) Pfam (PF17725) In PDB | Homo sapiens (Human) | TEA domain family member 4,TEAD-4,Transcription factor 13-like 1,Transcription factor RTEF-1 |
| 2 | L, M | Transcriptional coactivator YAP1 | polymer | 41 | 4650.3 | 2 | UniProt (P46937) Pfam (PF15238) In PDB | Homo sapiens | Yes-associated protein 1,Protein yorkie homolog,Yes-associated protein YAP65 homolog |
| 3 | A, B | MYRISTIC ACID | non-polymer | 228.4 | 2 | Chemie (MYR) | |||
| 4 | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence modifications
A, B: 216 - 434 (UniProt: Q15561)
| PDB | External Database | Details |
|---|---|---|
| Phe 429 | Tyr 429 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 60270.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 456.7 | |
| All* | Total formula weight | 60726.8 |
