6GEK

TEAD4 (216-434);Y429F COMPLEXED WITH YAP PEPTIDE (60-100) AND MYRISTOATE (COVALENTLY BOUND) AT 2.28A (P212121 CRYSTAL FORM); MYRISTOYLATION WAS DONE BY ADDING MYR-COA

Summary for 6GEK

Entry DOI	10.2210/pdb6gek/pdb
Related	6GE3 6GE4 6GE5 6GE6 6GEC 6GEE 6GEG 6GEI
Descriptor	Transcriptional enhancer factor TEF-3, Transcriptional coactivator YAP1, MYRISTIC ACID, ... (4 entities in total)
Functional Keywords	transcription, co-activator complex, protein-protein interaction
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	60726.80
Authors	Kallen, J. (deposition date: 2018-04-26, release date: 2018-09-19, Last modification date: 2024-01-17)
Primary citation	Mesrouze, Y.,Bokhovchuk, F.,Izaac, A.,Meyerhofer, M.,Zimmermann, C.,Fontana, P.,Schmelzle, T.,Erdmann, D.,Furet, P.,Kallen, J.,Chene, P. Adaptation of the bound intrinsically disordered protein YAP to mutations at the YAP:TEAD interface. Protein Sci., 27:1810-1820, 2018 Cited by PubMed: 30058229 DOI: 10.1002/pro.3493 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.28 Å)

Structure validation