6GE5
TEAD4 (216-434);Y429F COMPLEXED WITH YAP PEPTIDE (60-100) AND MYRISTOATE (COVALENTLY BOUND) AT 2.05A (P41212 CRYSTAL FORM); MYRISTOYLATION WAS DONE BY ADDING MYR-COA
Summary for 6GE5
Entry DOI | 10.2210/pdb6ge5/pdb |
Related | 6GE3 6GE4 |
Descriptor | Transcriptional enhancer factor TEF-3, Transcriptional coactivator YAP1, MYRISTIC ACID, ... (4 entities in total) |
Functional Keywords | transcription, co-activator, protein-protein interaction |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 30363.40 |
Authors | Kallen, J. (deposition date: 2018-04-25, release date: 2018-09-19, Last modification date: 2024-01-17) |
Primary citation | Mesrouze, Y.,Bokhovchuk, F.,Izaac, A.,Meyerhofer, M.,Zimmermann, C.,Fontana, P.,Schmelzle, T.,Erdmann, D.,Furet, P.,Kallen, J.,Chene, P. Adaptation of the bound intrinsically disordered protein YAP to mutations at the YAP:TEAD interface. Protein Sci., 27:1810-1820, 2018 Cited by PubMed: 30058229DOI: 10.1002/pro.3493 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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