6FP6

Complex of human Cu,Zn SOD1 with the human copper chaperone for SOD1 in a compact conformation

Summary for 6FP6

Entry DOI	10.2210/pdb6fp6/pdb
Descriptor	Superoxide dismutase [Cu-Zn], Copper chaperone for superoxide dismutase, ZINC ION, ... (6 entities in total)
Functional Keywords	heterodimer, copper-chaperone, hsod1, protein maturation, metal binding protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	24
Total formula weight	538996.42
Authors	Sala, F.A.,Wright, G.S.A.,Antonyuk, S.V.,Garratt, R.C.,Hasnain, S.S. (deposition date: 2018-02-09, release date: 2019-01-30, Last modification date: 2024-01-17)
Primary citation	Sala, F.A.,Wright, G.S.A.,Antonyuk, S.V.,Garratt, R.C.,Hasnain, S.S. Molecular recognition and maturation of SOD1 by its evolutionarily destabilised cognate chaperone hCCS. Plos Biol., 17:e3000141-e3000141, 2019 Cited by PubMed: 30735496 DOI: 10.1371/journal.pbio.3000141 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation