6FP6

Complex of human Cu,Zn SOD1 with the human copper chaperone for SOD1 in a compact conformation

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000302	biological_process	response to reactive oxygen species
A	0000303	biological_process	response to superoxide
A	0001541	biological_process	ovarian follicle development
A	0001819	biological_process	positive regulation of cytokine production
A	0001890	biological_process	placenta development
A	0001895	biological_process	retina homeostasis
A	0001975	biological_process	response to amphetamine
A	0002262	biological_process	myeloid cell homeostasis
A	0004784	molecular_function	superoxide dismutase activity
A	0005507	molecular_function	copper ion binding
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005758	cellular_component	mitochondrial intermembrane space
A	0005759	cellular_component	mitochondrial matrix
A	0005764	cellular_component	lysosome
A	0005777	cellular_component	peroxisome
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006749	biological_process	glutathione metabolic process
A	0006801	biological_process	superoxide metabolic process
A	0006879	biological_process	intracellular iron ion homeostasis
A	0006915	biological_process	apoptotic process
A	0006979	biological_process	response to oxidative stress
A	0007283	biological_process	spermatogenesis
A	0007566	biological_process	embryo implantation
A	0007605	biological_process	sensory perception of sound
A	0007626	biological_process	locomotory behavior
A	0008089	biological_process	anterograde axonal transport
A	0008090	biological_process	retrograde axonal transport
A	0008217	biological_process	regulation of blood pressure
A	0008270	molecular_function	zinc ion binding
A	0008340	biological_process	determination of adult lifespan
A	0009408	biological_process	response to heat
A	0009410	biological_process	response to xenobiotic stimulus
A	0010467	biological_process	gene expression
A	0016209	molecular_function	antioxidant activity
A	0016491	molecular_function	oxidoreductase activity
A	0019226	biological_process	transmission of nerve impulse
A	0019228	biological_process	neuronal action potential
A	0019430	biological_process	removal of superoxide radicals
A	0019899	molecular_function	enzyme binding
A	0030141	cellular_component	secretory granule
A	0030346	molecular_function	protein phosphatase 2B binding
A	0031045	cellular_component	dense core granule
A	0031267	molecular_function	small GTPase binding
A	0031410	cellular_component	cytoplasmic vesicle
A	0031667	biological_process	response to nutrient levels
A	0032287	biological_process	peripheral nervous system myelin maintenance
A	0032839	cellular_component	dendrite cytoplasm
A	0032930	biological_process	positive regulation of superoxide anion generation
A	0032991	cellular_component	protein-containing complex
A	0033081	biological_process	regulation of T cell differentiation in thymus
A	0034465	biological_process	response to carbon monoxide
A	0034599	biological_process	cellular response to oxidative stress
A	0035234	biological_process	ectopic germ cell programmed cell death
A	0035865	biological_process	cellular response to potassium ion
A	0040014	biological_process	regulation of multicellular organism growth
A	0042542	biological_process	response to hydrogen peroxide
A	0042554	biological_process	superoxide anion generation
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0043025	cellular_component	neuronal cell body
A	0043065	biological_process	positive regulation of apoptotic process
A	0043066	biological_process	negative regulation of apoptotic process
A	0043087	biological_process	regulation of GTPase activity
A	0043410	biological_process	positive regulation of MAPK cascade
A	0043524	biological_process	negative regulation of neuron apoptotic process
A	0045471	biological_process	response to ethanol
A	0046620	biological_process	regulation of organ growth
A	0046688	biological_process	response to copper ion
A	0046716	biological_process	muscle cell cellular homeostasis
A	0046872	molecular_function	metal ion binding
A	0048538	biological_process	thymus development
A	0048678	biological_process	response to axon injury
A	0050665	biological_process	hydrogen peroxide biosynthetic process
A	0050728	biological_process	negative regulation of inflammatory response
A	0050766	biological_process	positive regulation of phagocytosis
A	0051087	molecular_function	protein-folding chaperone binding
A	0051093	biological_process	negative regulation of developmental process
A	0051881	biological_process	regulation of mitochondrial membrane potential
A	0060047	biological_process	heart contraction
A	0060052	biological_process	neurofilament cytoskeleton organization
A	0060087	biological_process	relaxation of vascular associated smooth muscle
A	0060088	biological_process	auditory receptor cell stereocilium organization
A	0070062	cellular_component	extracellular exosome
A	0071276	biological_process	cellular response to cadmium ion
A	0071318	biological_process	cellular response to ATP
A	0072593	biological_process	reactive oxygen species metabolic process
A	0097332	biological_process	response to antipsychotic drug
A	0099610	biological_process	action potential initiation
A	1902177	biological_process	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
A	1904115	cellular_component	axon cytoplasm
A	2000242	biological_process	negative regulation of reproductive process
B	0005507	molecular_function	copper ion binding
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005829	cellular_component	cytosol
B	0006801	biological_process	superoxide metabolic process
B	0015035	molecular_function	protein-disulfide reductase activity
B	0016532	molecular_function	superoxide dismutase copper chaperone activity
B	0019430	biological_process	removal of superoxide radicals
B	0034599	biological_process	cellular response to oxidative stress
B	0045296	molecular_function	cadherin binding
B	0046872	molecular_function	metal ion binding
B	0051604	biological_process	protein maturation
C	0000302	biological_process	response to reactive oxygen species
C	0000303	biological_process	response to superoxide
C	0001541	biological_process	ovarian follicle development
C	0001819	biological_process	positive regulation of cytokine production
C	0001890	biological_process	placenta development
C	0001895	biological_process	retina homeostasis
C	0001975	biological_process	response to amphetamine
C	0002262	biological_process	myeloid cell homeostasis
C	0004784	molecular_function	superoxide dismutase activity
C	0005507	molecular_function	copper ion binding
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005758	cellular_component	mitochondrial intermembrane space
C	0005759	cellular_component	mitochondrial matrix
C	0005764	cellular_component	lysosome
C	0005777	cellular_component	peroxisome
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0006749	biological_process	glutathione metabolic process
C	0006801	biological_process	superoxide metabolic process
C	0006879	biological_process	intracellular iron ion homeostasis
C	0006915	biological_process	apoptotic process
C	0006979	biological_process	response to oxidative stress
C	0007283	biological_process	spermatogenesis
C	0007566	biological_process	embryo implantation
C	0007605	biological_process	sensory perception of sound
C	0007626	biological_process	locomotory behavior
C	0008089	biological_process	anterograde axonal transport
C	0008090	biological_process	retrograde axonal transport
C	0008217	biological_process	regulation of blood pressure
C	0008270	molecular_function	zinc ion binding
C	0008340	biological_process	determination of adult lifespan
C	0009408	biological_process	response to heat
C	0009410	biological_process	response to xenobiotic stimulus
C	0010467	biological_process	gene expression
C	0016209	molecular_function	antioxidant activity
C	0016491	molecular_function	oxidoreductase activity
C	0019226	biological_process	transmission of nerve impulse
C	0019228	biological_process	neuronal action potential
C	0019430	biological_process	removal of superoxide radicals
C	0019899	molecular_function	enzyme binding
C	0030141	cellular_component	secretory granule
C	0030346	molecular_function	protein phosphatase 2B binding
C	0031045	cellular_component	dense core granule
C	0031267	molecular_function	small GTPase binding
C	0031410	cellular_component	cytoplasmic vesicle
C	0031667	biological_process	response to nutrient levels
C	0032287	biological_process	peripheral nervous system myelin maintenance
C	0032839	cellular_component	dendrite cytoplasm
C	0032930	biological_process	positive regulation of superoxide anion generation
C	0032991	cellular_component	protein-containing complex
C	0033081	biological_process	regulation of T cell differentiation in thymus
C	0034465	biological_process	response to carbon monoxide
C	0034599	biological_process	cellular response to oxidative stress
C	0035234	biological_process	ectopic germ cell programmed cell death
C	0035865	biological_process	cellular response to potassium ion
C	0040014	biological_process	regulation of multicellular organism growth
C	0042542	biological_process	response to hydrogen peroxide
C	0042554	biological_process	superoxide anion generation
C	0042802	molecular_function	identical protein binding
C	0042803	molecular_function	protein homodimerization activity
C	0043025	cellular_component	neuronal cell body
C	0043065	biological_process	positive regulation of apoptotic process
C	0043066	biological_process	negative regulation of apoptotic process
C	0043087	biological_process	regulation of GTPase activity
C	0043410	biological_process	positive regulation of MAPK cascade
C	0043524	biological_process	negative regulation of neuron apoptotic process
C	0045471	biological_process	response to ethanol
C	0046620	biological_process	regulation of organ growth
C	0046688	biological_process	response to copper ion
C	0046716	biological_process	muscle cell cellular homeostasis
C	0046872	molecular_function	metal ion binding
C	0048538	biological_process	thymus development
C	0048678	biological_process	response to axon injury
C	0050665	biological_process	hydrogen peroxide biosynthetic process
C	0050728	biological_process	negative regulation of inflammatory response
C	0050766	biological_process	positive regulation of phagocytosis
C	0051087	molecular_function	protein-folding chaperone binding
C	0051093	biological_process	negative regulation of developmental process
C	0051881	biological_process	regulation of mitochondrial membrane potential
C	0060047	biological_process	heart contraction
C	0060052	biological_process	neurofilament cytoskeleton organization
C	0060087	biological_process	relaxation of vascular associated smooth muscle
C	0060088	biological_process	auditory receptor cell stereocilium organization
C	0070062	cellular_component	extracellular exosome
C	0071276	biological_process	cellular response to cadmium ion
C	0071318	biological_process	cellular response to ATP
C	0072593	biological_process	reactive oxygen species metabolic process
C	0097332	biological_process	response to antipsychotic drug
C	0099610	biological_process	action potential initiation
C	1902177	biological_process	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
C	1904115	cellular_component	axon cytoplasm
C	2000242	biological_process	negative regulation of reproductive process
D	0005507	molecular_function	copper ion binding
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005829	cellular_component	cytosol
D	0006801	biological_process	superoxide metabolic process
D	0015035	molecular_function	protein-disulfide reductase activity
D	0016532	molecular_function	superoxide dismutase copper chaperone activity
D	0019430	biological_process	removal of superoxide radicals
D	0034599	biological_process	cellular response to oxidative stress
D	0045296	molecular_function	cadherin binding
D	0046872	molecular_function	metal ion binding
D	0051604	biological_process	protein maturation
E	0000302	biological_process	response to reactive oxygen species
E	0000303	biological_process	response to superoxide
E	0001541	biological_process	ovarian follicle development
E	0001819	biological_process	positive regulation of cytokine production
E	0001890	biological_process	placenta development
E	0001895	biological_process	retina homeostasis
E	0001975	biological_process	response to amphetamine
E	0002262	biological_process	myeloid cell homeostasis
E	0004784	molecular_function	superoxide dismutase activity
E	0005507	molecular_function	copper ion binding
E	0005515	molecular_function	protein binding
E	0005576	cellular_component	extracellular region
E	0005615	cellular_component	extracellular space
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0005758	cellular_component	mitochondrial intermembrane space
E	0005759	cellular_component	mitochondrial matrix
E	0005764	cellular_component	lysosome
E	0005777	cellular_component	peroxisome
E	0005829	cellular_component	cytosol
E	0005886	cellular_component	plasma membrane
E	0006749	biological_process	glutathione metabolic process
E	0006801	biological_process	superoxide metabolic process
E	0006879	biological_process	intracellular iron ion homeostasis
E	0006915	biological_process	apoptotic process
E	0006979	biological_process	response to oxidative stress
E	0007283	biological_process	spermatogenesis
E	0007566	biological_process	embryo implantation
E	0007605	biological_process	sensory perception of sound
E	0007626	biological_process	locomotory behavior
E	0008089	biological_process	anterograde axonal transport
E	0008090	biological_process	retrograde axonal transport
E	0008217	biological_process	regulation of blood pressure
E	0008270	molecular_function	zinc ion binding
E	0008340	biological_process	determination of adult lifespan
E	0009408	biological_process	response to heat
E	0009410	biological_process	response to xenobiotic stimulus
E	0010467	biological_process	gene expression
E	0016209	molecular_function	antioxidant activity
E	0016491	molecular_function	oxidoreductase activity
E	0019226	biological_process	transmission of nerve impulse
E	0019228	biological_process	neuronal action potential
E	0019430	biological_process	removal of superoxide radicals
E	0019899	molecular_function	enzyme binding
E	0030141	cellular_component	secretory granule
E	0030346	molecular_function	protein phosphatase 2B binding
E	0031045	cellular_component	dense core granule
E	0031267	molecular_function	small GTPase binding
E	0031410	cellular_component	cytoplasmic vesicle
E	0031667	biological_process	response to nutrient levels
E	0032287	biological_process	peripheral nervous system myelin maintenance
E	0032839	cellular_component	dendrite cytoplasm
E	0032930	biological_process	positive regulation of superoxide anion generation
E	0032991	cellular_component	protein-containing complex
E	0033081	biological_process	regulation of T cell differentiation in thymus
E	0034465	biological_process	response to carbon monoxide
E	0034599	biological_process	cellular response to oxidative stress
E	0035234	biological_process	ectopic germ cell programmed cell death
E	0035865	biological_process	cellular response to potassium ion
E	0040014	biological_process	regulation of multicellular organism growth
E	0042542	biological_process	response to hydrogen peroxide
E	0042554	biological_process	superoxide anion generation
E	0042802	molecular_function	identical protein binding
E	0042803	molecular_function	protein homodimerization activity
E	0043025	cellular_component	neuronal cell body
E	0043065	biological_process	positive regulation of apoptotic process
E	0043066	biological_process	negative regulation of apoptotic process
E	0043087	biological_process	regulation of GTPase activity
E	0043410	biological_process	positive regulation of MAPK cascade
E	0043524	biological_process	negative regulation of neuron apoptotic process
E	0045471	biological_process	response to ethanol
E	0046620	biological_process	regulation of organ growth
E	0046688	biological_process	response to copper ion
E	0046716	biological_process	muscle cell cellular homeostasis
E	0046872	molecular_function	metal ion binding
E	0048538	biological_process	thymus development
E	0048678	biological_process	response to axon injury
E	0050665	biological_process	hydrogen peroxide biosynthetic process
E	0050728	biological_process	negative regulation of inflammatory response
E	0050766	biological_process	positive regulation of phagocytosis
E	0051087	molecular_function	protein-folding chaperone binding
E	0051093	biological_process	negative regulation of developmental process
E	0051881	biological_process	regulation of mitochondrial membrane potential
E	0060047	biological_process	heart contraction
E	0060052	biological_process	neurofilament cytoskeleton organization
E	0060087	biological_process	relaxation of vascular associated smooth muscle
E	0060088	biological_process	auditory receptor cell stereocilium organization
E	0070062	cellular_component	extracellular exosome
E	0071276	biological_process	cellular response to cadmium ion
E	0071318	biological_process	cellular response to ATP
E	0072593	biological_process	reactive oxygen species metabolic process
E	0097332	biological_process	response to antipsychotic drug
E	0099610	biological_process	action potential initiation
E	1902177	biological_process	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
E	1904115	cellular_component	axon cytoplasm
E	2000242	biological_process	negative regulation of reproductive process
F	0005507	molecular_function	copper ion binding
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005737	cellular_component	cytoplasm
F	0005739	cellular_component	mitochondrion
F	0005829	cellular_component	cytosol
F	0006801	biological_process	superoxide metabolic process
F	0015035	molecular_function	protein-disulfide reductase activity
F	0016532	molecular_function	superoxide dismutase copper chaperone activity
F	0019430	biological_process	removal of superoxide radicals
F	0034599	biological_process	cellular response to oxidative stress
F	0045296	molecular_function	cadherin binding
F	0046872	molecular_function	metal ion binding
F	0051604	biological_process	protein maturation
G	0000302	biological_process	response to reactive oxygen species
G	0000303	biological_process	response to superoxide
G	0001541	biological_process	ovarian follicle development
G	0001819	biological_process	positive regulation of cytokine production
G	0001890	biological_process	placenta development
G	0001895	biological_process	retina homeostasis
G	0001975	biological_process	response to amphetamine
G	0002262	biological_process	myeloid cell homeostasis
G	0004784	molecular_function	superoxide dismutase activity
G	0005507	molecular_function	copper ion binding
G	0005515	molecular_function	protein binding
G	0005576	cellular_component	extracellular region
G	0005615	cellular_component	extracellular space
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005737	cellular_component	cytoplasm
G	0005739	cellular_component	mitochondrion
G	0005758	cellular_component	mitochondrial intermembrane space
G	0005759	cellular_component	mitochondrial matrix
G	0005764	cellular_component	lysosome
G	0005777	cellular_component	peroxisome
G	0005829	cellular_component	cytosol
G	0005886	cellular_component	plasma membrane
G	0006749	biological_process	glutathione metabolic process
G	0006801	biological_process	superoxide metabolic process
G	0006879	biological_process	intracellular iron ion homeostasis
G	0006915	biological_process	apoptotic process
G	0006979	biological_process	response to oxidative stress
G	0007283	biological_process	spermatogenesis
G	0007566	biological_process	embryo implantation
G	0007605	biological_process	sensory perception of sound
G	0007626	biological_process	locomotory behavior
G	0008089	biological_process	anterograde axonal transport
G	0008090	biological_process	retrograde axonal transport
G	0008217	biological_process	regulation of blood pressure
G	0008270	molecular_function	zinc ion binding
G	0008340	biological_process	determination of adult lifespan
G	0009408	biological_process	response to heat
G	0009410	biological_process	response to xenobiotic stimulus
G	0010467	biological_process	gene expression
G	0016209	molecular_function	antioxidant activity
G	0016491	molecular_function	oxidoreductase activity
G	0019226	biological_process	transmission of nerve impulse
G	0019228	biological_process	neuronal action potential
G	0019430	biological_process	removal of superoxide radicals
G	0019899	molecular_function	enzyme binding
G	0030141	cellular_component	secretory granule
G	0030346	molecular_function	protein phosphatase 2B binding
G	0031045	cellular_component	dense core granule
G	0031267	molecular_function	small GTPase binding
G	0031410	cellular_component	cytoplasmic vesicle
G	0031667	biological_process	response to nutrient levels
G	0032287	biological_process	peripheral nervous system myelin maintenance
G	0032839	cellular_component	dendrite cytoplasm
G	0032930	biological_process	positive regulation of superoxide anion generation
G	0032991	cellular_component	protein-containing complex
G	0033081	biological_process	regulation of T cell differentiation in thymus
G	0034465	biological_process	response to carbon monoxide
G	0034599	biological_process	cellular response to oxidative stress
G	0035234	biological_process	ectopic germ cell programmed cell death
G	0035865	biological_process	cellular response to potassium ion
G	0040014	biological_process	regulation of multicellular organism growth
G	0042542	biological_process	response to hydrogen peroxide
G	0042554	biological_process	superoxide anion generation
G	0042802	molecular_function	identical protein binding
G	0042803	molecular_function	protein homodimerization activity
G	0043025	cellular_component	neuronal cell body
G	0043065	biological_process	positive regulation of apoptotic process
G	0043066	biological_process	negative regulation of apoptotic process
G	0043087	biological_process	regulation of GTPase activity
G	0043410	biological_process	positive regulation of MAPK cascade
G	0043524	biological_process	negative regulation of neuron apoptotic process
G	0045471	biological_process	response to ethanol
G	0046620	biological_process	regulation of organ growth
G	0046688	biological_process	response to copper ion
G	0046716	biological_process	muscle cell cellular homeostasis
G	0046872	molecular_function	metal ion binding
G	0048538	biological_process	thymus development
G	0048678	biological_process	response to axon injury
G	0050665	biological_process	hydrogen peroxide biosynthetic process
G	0050728	biological_process	negative regulation of inflammatory response
G	0050766	biological_process	positive regulation of phagocytosis
G	0051087	molecular_function	protein-folding chaperone binding
G	0051093	biological_process	negative regulation of developmental process
G	0051881	biological_process	regulation of mitochondrial membrane potential
G	0060047	biological_process	heart contraction
G	0060052	biological_process	neurofilament cytoskeleton organization
G	0060087	biological_process	relaxation of vascular associated smooth muscle
G	0060088	biological_process	auditory receptor cell stereocilium organization
G	0070062	cellular_component	extracellular exosome
G	0071276	biological_process	cellular response to cadmium ion
G	0071318	biological_process	cellular response to ATP
G	0072593	biological_process	reactive oxygen species metabolic process
G	0097332	biological_process	response to antipsychotic drug
G	0099610	biological_process	action potential initiation
G	1902177	biological_process	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
G	1904115	cellular_component	axon cytoplasm
G	2000242	biological_process	negative regulation of reproductive process
H	0005507	molecular_function	copper ion binding
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005737	cellular_component	cytoplasm
H	0005739	cellular_component	mitochondrion
H	0005829	cellular_component	cytosol
H	0006801	biological_process	superoxide metabolic process
H	0015035	molecular_function	protein-disulfide reductase activity
H	0016532	molecular_function	superoxide dismutase copper chaperone activity
H	0019430	biological_process	removal of superoxide radicals
H	0034599	biological_process	cellular response to oxidative stress
H	0045296	molecular_function	cadherin binding
H	0046872	molecular_function	metal ion binding
H	0051604	biological_process	protein maturation
I	0000302	biological_process	response to reactive oxygen species
I	0000303	biological_process	response to superoxide
I	0001541	biological_process	ovarian follicle development
I	0001819	biological_process	positive regulation of cytokine production
I	0001890	biological_process	placenta development
I	0001895	biological_process	retina homeostasis
I	0001975	biological_process	response to amphetamine
I	0002262	biological_process	myeloid cell homeostasis
I	0004784	molecular_function	superoxide dismutase activity
I	0005507	molecular_function	copper ion binding
I	0005515	molecular_function	protein binding
I	0005576	cellular_component	extracellular region
I	0005615	cellular_component	extracellular space
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005737	cellular_component	cytoplasm
I	0005739	cellular_component	mitochondrion
I	0005758	cellular_component	mitochondrial intermembrane space
I	0005759	cellular_component	mitochondrial matrix
I	0005764	cellular_component	lysosome
I	0005777	cellular_component	peroxisome
I	0005829	cellular_component	cytosol
I	0005886	cellular_component	plasma membrane
I	0006749	biological_process	glutathione metabolic process
I	0006801	biological_process	superoxide metabolic process
I	0006879	biological_process	intracellular iron ion homeostasis
I	0006915	biological_process	apoptotic process
I	0006979	biological_process	response to oxidative stress
I	0007283	biological_process	spermatogenesis
I	0007566	biological_process	embryo implantation
I	0007605	biological_process	sensory perception of sound
I	0007626	biological_process	locomotory behavior
I	0008089	biological_process	anterograde axonal transport
I	0008090	biological_process	retrograde axonal transport
I	0008217	biological_process	regulation of blood pressure
I	0008270	molecular_function	zinc ion binding
I	0008340	biological_process	determination of adult lifespan
I	0009408	biological_process	response to heat
I	0009410	biological_process	response to xenobiotic stimulus
I	0010467	biological_process	gene expression
I	0016209	molecular_function	antioxidant activity
I	0016491	molecular_function	oxidoreductase activity
I	0019226	biological_process	transmission of nerve impulse
I	0019228	biological_process	neuronal action potential
I	0019430	biological_process	removal of superoxide radicals
I	0019899	molecular_function	enzyme binding
I	0030141	cellular_component	secretory granule
I	0030346	molecular_function	protein phosphatase 2B binding
I	0031045	cellular_component	dense core granule
I	0031267	molecular_function	small GTPase binding
I	0031410	cellular_component	cytoplasmic vesicle
I	0031667	biological_process	response to nutrient levels
I	0032287	biological_process	peripheral nervous system myelin maintenance
I	0032839	cellular_component	dendrite cytoplasm
I	0032930	biological_process	positive regulation of superoxide anion generation
I	0032991	cellular_component	protein-containing complex
I	0033081	biological_process	regulation of T cell differentiation in thymus
I	0034465	biological_process	response to carbon monoxide
I	0034599	biological_process	cellular response to oxidative stress
I	0035234	biological_process	ectopic germ cell programmed cell death
I	0035865	biological_process	cellular response to potassium ion
I	0040014	biological_process	regulation of multicellular organism growth
I	0042542	biological_process	response to hydrogen peroxide
I	0042554	biological_process	superoxide anion generation
I	0042802	molecular_function	identical protein binding
I	0042803	molecular_function	protein homodimerization activity
I	0043025	cellular_component	neuronal cell body
I	0043065	biological_process	positive regulation of apoptotic process
I	0043066	biological_process	negative regulation of apoptotic process
I	0043087	biological_process	regulation of GTPase activity
I	0043410	biological_process	positive regulation of MAPK cascade
I	0043524	biological_process	negative regulation of neuron apoptotic process
I	0045471	biological_process	response to ethanol
I	0046620	biological_process	regulation of organ growth
I	0046688	biological_process	response to copper ion
I	0046716	biological_process	muscle cell cellular homeostasis
I	0046872	molecular_function	metal ion binding
I	0048538	biological_process	thymus development
I	0048678	biological_process	response to axon injury
I	0050665	biological_process	hydrogen peroxide biosynthetic process
I	0050728	biological_process	negative regulation of inflammatory response
I	0050766	biological_process	positive regulation of phagocytosis
I	0051087	molecular_function	protein-folding chaperone binding
I	0051093	biological_process	negative regulation of developmental process
I	0051881	biological_process	regulation of mitochondrial membrane potential
I	0060047	biological_process	heart contraction
I	0060052	biological_process	neurofilament cytoskeleton organization
I	0060087	biological_process	relaxation of vascular associated smooth muscle
I	0060088	biological_process	auditory receptor cell stereocilium organization
I	0070062	cellular_component	extracellular exosome
I	0071276	biological_process	cellular response to cadmium ion
I	0071318	biological_process	cellular response to ATP
I	0072593	biological_process	reactive oxygen species metabolic process
I	0097332	biological_process	response to antipsychotic drug
I	0099610	biological_process	action potential initiation
I	1902177	biological_process	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
I	1904115	cellular_component	axon cytoplasm
I	2000242	biological_process	negative regulation of reproductive process
J	0005507	molecular_function	copper ion binding
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005737	cellular_component	cytoplasm
J	0005739	cellular_component	mitochondrion
J	0005829	cellular_component	cytosol
J	0006801	biological_process	superoxide metabolic process
J	0015035	molecular_function	protein-disulfide reductase activity
J	0016532	molecular_function	superoxide dismutase copper chaperone activity
J	0019430	biological_process	removal of superoxide radicals
J	0034599	biological_process	cellular response to oxidative stress
J	0045296	molecular_function	cadherin binding
J	0046872	molecular_function	metal ion binding
J	0051604	biological_process	protein maturation
K	0000302	biological_process	response to reactive oxygen species
K	0000303	biological_process	response to superoxide
K	0001541	biological_process	ovarian follicle development
K	0001819	biological_process	positive regulation of cytokine production
K	0001890	biological_process	placenta development
K	0001895	biological_process	retina homeostasis
K	0001975	biological_process	response to amphetamine
K	0002262	biological_process	myeloid cell homeostasis
K	0004784	molecular_function	superoxide dismutase activity
K	0005507	molecular_function	copper ion binding
K	0005515	molecular_function	protein binding
K	0005576	cellular_component	extracellular region
K	0005615	cellular_component	extracellular space
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005737	cellular_component	cytoplasm
K	0005739	cellular_component	mitochondrion
K	0005758	cellular_component	mitochondrial intermembrane space
K	0005759	cellular_component	mitochondrial matrix
K	0005764	cellular_component	lysosome
K	0005777	cellular_component	peroxisome
K	0005829	cellular_component	cytosol
K	0005886	cellular_component	plasma membrane
K	0006749	biological_process	glutathione metabolic process
K	0006801	biological_process	superoxide metabolic process
K	0006879	biological_process	intracellular iron ion homeostasis
K	0006915	biological_process	apoptotic process
K	0006979	biological_process	response to oxidative stress
K	0007283	biological_process	spermatogenesis
K	0007566	biological_process	embryo implantation
K	0007605	biological_process	sensory perception of sound
K	0007626	biological_process	locomotory behavior
K	0008089	biological_process	anterograde axonal transport
K	0008090	biological_process	retrograde axonal transport
K	0008217	biological_process	regulation of blood pressure
K	0008270	molecular_function	zinc ion binding
K	0008340	biological_process	determination of adult lifespan
K	0009408	biological_process	response to heat
K	0009410	biological_process	response to xenobiotic stimulus
K	0010467	biological_process	gene expression
K	0016209	molecular_function	antioxidant activity
K	0016491	molecular_function	oxidoreductase activity
K	0019226	biological_process	transmission of nerve impulse
K	0019228	biological_process	neuronal action potential
K	0019430	biological_process	removal of superoxide radicals
K	0019899	molecular_function	enzyme binding
K	0030141	cellular_component	secretory granule
K	0030346	molecular_function	protein phosphatase 2B binding
K	0031045	cellular_component	dense core granule
K	0031267	molecular_function	small GTPase binding
K	0031410	cellular_component	cytoplasmic vesicle
K	0031667	biological_process	response to nutrient levels
K	0032287	biological_process	peripheral nervous system myelin maintenance
K	0032839	cellular_component	dendrite cytoplasm
K	0032930	biological_process	positive regulation of superoxide anion generation
K	0032991	cellular_component	protein-containing complex
K	0033081	biological_process	regulation of T cell differentiation in thymus
K	0034465	biological_process	response to carbon monoxide
K	0034599	biological_process	cellular response to oxidative stress
K	0035234	biological_process	ectopic germ cell programmed cell death
K	0035865	biological_process	cellular response to potassium ion
K	0040014	biological_process	regulation of multicellular organism growth
K	0042542	biological_process	response to hydrogen peroxide
K	0042554	biological_process	superoxide anion generation
K	0042802	molecular_function	identical protein binding
K	0042803	molecular_function	protein homodimerization activity
K	0043025	cellular_component	neuronal cell body
K	0043065	biological_process	positive regulation of apoptotic process
K	0043066	biological_process	negative regulation of apoptotic process
K	0043087	biological_process	regulation of GTPase activity
K	0043410	biological_process	positive regulation of MAPK cascade
K	0043524	biological_process	negative regulation of neuron apoptotic process
K	0045471	biological_process	response to ethanol
K	0046620	biological_process	regulation of organ growth
K	0046688	biological_process	response to copper ion
K	0046716	biological_process	muscle cell cellular homeostasis
K	0046872	molecular_function	metal ion binding
K	0048538	biological_process	thymus development
K	0048678	biological_process	response to axon injury
K	0050665	biological_process	hydrogen peroxide biosynthetic process
K	0050728	biological_process	negative regulation of inflammatory response
K	0050766	biological_process	positive regulation of phagocytosis
K	0051087	molecular_function	protein-folding chaperone binding
K	0051093	biological_process	negative regulation of developmental process
K	0051881	biological_process	regulation of mitochondrial membrane potential
K	0060047	biological_process	heart contraction
K	0060052	biological_process	neurofilament cytoskeleton organization
K	0060087	biological_process	relaxation of vascular associated smooth muscle
K	0060088	biological_process	auditory receptor cell stereocilium organization
K	0070062	cellular_component	extracellular exosome
K	0071276	biological_process	cellular response to cadmium ion
K	0071318	biological_process	cellular response to ATP
K	0072593	biological_process	reactive oxygen species metabolic process
K	0097332	biological_process	response to antipsychotic drug
K	0099610	biological_process	action potential initiation
K	1902177	biological_process	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
K	1904115	cellular_component	axon cytoplasm
K	2000242	biological_process	negative regulation of reproductive process
L	0005507	molecular_function	copper ion binding
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005737	cellular_component	cytoplasm
L	0005739	cellular_component	mitochondrion
L	0005829	cellular_component	cytosol
L	0006801	biological_process	superoxide metabolic process
L	0015035	molecular_function	protein-disulfide reductase activity
L	0016532	molecular_function	superoxide dismutase copper chaperone activity
L	0019430	biological_process	removal of superoxide radicals
L	0034599	biological_process	cellular response to oxidative stress
L	0045296	molecular_function	cadherin binding
L	0046872	molecular_function	metal ion binding
L	0051604	biological_process	protein maturation
M	0000302	biological_process	response to reactive oxygen species
M	0000303	biological_process	response to superoxide
M	0001541	biological_process	ovarian follicle development
M	0001819	biological_process	positive regulation of cytokine production
M	0001890	biological_process	placenta development
M	0001895	biological_process	retina homeostasis
M	0001975	biological_process	response to amphetamine
M	0002262	biological_process	myeloid cell homeostasis
M	0004784	molecular_function	superoxide dismutase activity
M	0005507	molecular_function	copper ion binding
M	0005515	molecular_function	protein binding
M	0005576	cellular_component	extracellular region
M	0005615	cellular_component	extracellular space
M	0005634	cellular_component	nucleus
M	0005654	cellular_component	nucleoplasm
M	0005737	cellular_component	cytoplasm
M	0005739	cellular_component	mitochondrion
M	0005758	cellular_component	mitochondrial intermembrane space
M	0005759	cellular_component	mitochondrial matrix
M	0005764	cellular_component	lysosome
M	0005777	cellular_component	peroxisome
M	0005829	cellular_component	cytosol
M	0005886	cellular_component	plasma membrane
M	0006749	biological_process	glutathione metabolic process
M	0006801	biological_process	superoxide metabolic process
M	0006879	biological_process	intracellular iron ion homeostasis
M	0006915	biological_process	apoptotic process
M	0006979	biological_process	response to oxidative stress
M	0007283	biological_process	spermatogenesis
M	0007566	biological_process	embryo implantation
M	0007605	biological_process	sensory perception of sound
M	0007626	biological_process	locomotory behavior
M	0008089	biological_process	anterograde axonal transport
M	0008090	biological_process	retrograde axonal transport
M	0008217	biological_process	regulation of blood pressure
M	0008270	molecular_function	zinc ion binding
M	0008340	biological_process	determination of adult lifespan
M	0009408	biological_process	response to heat
M	0009410	biological_process	response to xenobiotic stimulus
M	0010467	biological_process	gene expression
M	0016209	molecular_function	antioxidant activity
M	0016491	molecular_function	oxidoreductase activity
M	0019226	biological_process	transmission of nerve impulse
M	0019228	biological_process	neuronal action potential
M	0019430	biological_process	removal of superoxide radicals
M	0019899	molecular_function	enzyme binding
M	0030141	cellular_component	secretory granule
M	0030346	molecular_function	protein phosphatase 2B binding
M	0031045	cellular_component	dense core granule
M	0031267	molecular_function	small GTPase binding
M	0031410	cellular_component	cytoplasmic vesicle
M	0031667	biological_process	response to nutrient levels
M	0032287	biological_process	peripheral nervous system myelin maintenance
M	0032839	cellular_component	dendrite cytoplasm
M	0032930	biological_process	positive regulation of superoxide anion generation
M	0032991	cellular_component	protein-containing complex
M	0033081	biological_process	regulation of T cell differentiation in thymus
M	0034465	biological_process	response to carbon monoxide
M	0034599	biological_process	cellular response to oxidative stress
M	0035234	biological_process	ectopic germ cell programmed cell death
M	0035865	biological_process	cellular response to potassium ion
M	0040014	biological_process	regulation of multicellular organism growth
M	0042542	biological_process	response to hydrogen peroxide
M	0042554	biological_process	superoxide anion generation
M	0042802	molecular_function	identical protein binding
M	0042803	molecular_function	protein homodimerization activity
M	0043025	cellular_component	neuronal cell body
M	0043065	biological_process	positive regulation of apoptotic process
M	0043066	biological_process	negative regulation of apoptotic process
M	0043087	biological_process	regulation of GTPase activity
M	0043410	biological_process	positive regulation of MAPK cascade
M	0043524	biological_process	negative regulation of neuron apoptotic process
M	0045471	biological_process	response to ethanol
M	0046620	biological_process	regulation of organ growth
M	0046688	biological_process	response to copper ion
M	0046716	biological_process	muscle cell cellular homeostasis
M	0046872	molecular_function	metal ion binding
M	0048538	biological_process	thymus development
M	0048678	biological_process	response to axon injury
M	0050665	biological_process	hydrogen peroxide biosynthetic process
M	0050728	biological_process	negative regulation of inflammatory response
M	0050766	biological_process	positive regulation of phagocytosis
M	0051087	molecular_function	protein-folding chaperone binding
M	0051093	biological_process	negative regulation of developmental process
M	0051881	biological_process	regulation of mitochondrial membrane potential
M	0060047	biological_process	heart contraction
M	0060052	biological_process	neurofilament cytoskeleton organization
M	0060087	biological_process	relaxation of vascular associated smooth muscle
M	0060088	biological_process	auditory receptor cell stereocilium organization
M	0070062	cellular_component	extracellular exosome
M	0071276	biological_process	cellular response to cadmium ion
M	0071318	biological_process	cellular response to ATP
M	0072593	biological_process	reactive oxygen species metabolic process
M	0097332	biological_process	response to antipsychotic drug
M	0099610	biological_process	action potential initiation
M	1902177	biological_process	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
M	1904115	cellular_component	axon cytoplasm
M	2000242	biological_process	negative regulation of reproductive process
N	0005507	molecular_function	copper ion binding
N	0005515	molecular_function	protein binding
N	0005634	cellular_component	nucleus
N	0005737	cellular_component	cytoplasm
N	0005739	cellular_component	mitochondrion
N	0005829	cellular_component	cytosol
N	0006801	biological_process	superoxide metabolic process
N	0015035	molecular_function	protein-disulfide reductase activity
N	0016532	molecular_function	superoxide dismutase copper chaperone activity
N	0019430	biological_process	removal of superoxide radicals
N	0034599	biological_process	cellular response to oxidative stress
N	0045296	molecular_function	cadherin binding
N	0046872	molecular_function	metal ion binding
N	0051604	biological_process	protein maturation
O	0000302	biological_process	response to reactive oxygen species
O	0000303	biological_process	response to superoxide
O	0001541	biological_process	ovarian follicle development
O	0001819	biological_process	positive regulation of cytokine production
O	0001890	biological_process	placenta development
O	0001895	biological_process	retina homeostasis
O	0001975	biological_process	response to amphetamine
O	0002262	biological_process	myeloid cell homeostasis
O	0004784	molecular_function	superoxide dismutase activity
O	0005507	molecular_function	copper ion binding
O	0005515	molecular_function	protein binding
O	0005576	cellular_component	extracellular region
O	0005615	cellular_component	extracellular space
O	0005634	cellular_component	nucleus
O	0005654	cellular_component	nucleoplasm
O	0005737	cellular_component	cytoplasm
O	0005739	cellular_component	mitochondrion
O	0005758	cellular_component	mitochondrial intermembrane space
O	0005759	cellular_component	mitochondrial matrix
O	0005764	cellular_component	lysosome
O	0005777	cellular_component	peroxisome
O	0005829	cellular_component	cytosol
O	0005886	cellular_component	plasma membrane
O	0006749	biological_process	glutathione metabolic process
O	0006801	biological_process	superoxide metabolic process
O	0006879	biological_process	intracellular iron ion homeostasis
O	0006915	biological_process	apoptotic process
O	0006979	biological_process	response to oxidative stress
O	0007283	biological_process	spermatogenesis
O	0007566	biological_process	embryo implantation
O	0007605	biological_process	sensory perception of sound
O	0007626	biological_process	locomotory behavior
O	0008089	biological_process	anterograde axonal transport
O	0008090	biological_process	retrograde axonal transport
O	0008217	biological_process	regulation of blood pressure
O	0008270	molecular_function	zinc ion binding
O	0008340	biological_process	determination of adult lifespan
O	0009408	biological_process	response to heat
O	0009410	biological_process	response to xenobiotic stimulus
O	0010467	biological_process	gene expression
O	0016209	molecular_function	antioxidant activity
O	0016491	molecular_function	oxidoreductase activity
O	0019226	biological_process	transmission of nerve impulse
O	0019228	biological_process	neuronal action potential
O	0019430	biological_process	removal of superoxide radicals
O	0019899	molecular_function	enzyme binding
O	0030141	cellular_component	secretory granule
O	0030346	molecular_function	protein phosphatase 2B binding
O	0031045	cellular_component	dense core granule
O	0031267	molecular_function	small GTPase binding
O	0031410	cellular_component	cytoplasmic vesicle
O	0031667	biological_process	response to nutrient levels
O	0032287	biological_process	peripheral nervous system myelin maintenance
O	0032839	cellular_component	dendrite cytoplasm
O	0032930	biological_process	positive regulation of superoxide anion generation
O	0032991	cellular_component	protein-containing complex
O	0033081	biological_process	regulation of T cell differentiation in thymus
O	0034465	biological_process	response to carbon monoxide
O	0034599	biological_process	cellular response to oxidative stress
O	0035234	biological_process	ectopic germ cell programmed cell death
O	0035865	biological_process	cellular response to potassium ion
O	0040014	biological_process	regulation of multicellular organism growth
O	0042542	biological_process	response to hydrogen peroxide
O	0042554	biological_process	superoxide anion generation
O	0042802	molecular_function	identical protein binding
O	0042803	molecular_function	protein homodimerization activity
O	0043025	cellular_component	neuronal cell body
O	0043065	biological_process	positive regulation of apoptotic process
O	0043066	biological_process	negative regulation of apoptotic process
O	0043087	biological_process	regulation of GTPase activity
O	0043410	biological_process	positive regulation of MAPK cascade
O	0043524	biological_process	negative regulation of neuron apoptotic process
O	0045471	biological_process	response to ethanol
O	0046620	biological_process	regulation of organ growth
O	0046688	biological_process	response to copper ion
O	0046716	biological_process	muscle cell cellular homeostasis
O	0046872	molecular_function	metal ion binding
O	0048538	biological_process	thymus development
O	0048678	biological_process	response to axon injury
O	0050665	biological_process	hydrogen peroxide biosynthetic process
O	0050728	biological_process	negative regulation of inflammatory response
O	0050766	biological_process	positive regulation of phagocytosis
O	0051087	molecular_function	protein-folding chaperone binding
O	0051093	biological_process	negative regulation of developmental process
O	0051881	biological_process	regulation of mitochondrial membrane potential
O	0060047	biological_process	heart contraction
O	0060052	biological_process	neurofilament cytoskeleton organization
O	0060087	biological_process	relaxation of vascular associated smooth muscle
O	0060088	biological_process	auditory receptor cell stereocilium organization
O	0070062	cellular_component	extracellular exosome
O	0071276	biological_process	cellular response to cadmium ion
O	0071318	biological_process	cellular response to ATP
O	0072593	biological_process	reactive oxygen species metabolic process
O	0097332	biological_process	response to antipsychotic drug
O	0099610	biological_process	action potential initiation
O	1902177	biological_process	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
O	1904115	cellular_component	axon cytoplasm
O	2000242	biological_process	negative regulation of reproductive process
P	0005507	molecular_function	copper ion binding
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005737	cellular_component	cytoplasm
P	0005739	cellular_component	mitochondrion
P	0005829	cellular_component	cytosol
P	0006801	biological_process	superoxide metabolic process
P	0015035	molecular_function	protein-disulfide reductase activity
P	0016532	molecular_function	superoxide dismutase copper chaperone activity
P	0019430	biological_process	removal of superoxide radicals
P	0034599	biological_process	cellular response to oxidative stress
P	0045296	molecular_function	cadherin binding
P	0046872	molecular_function	metal ion binding
P	0051604	biological_process	protein maturation
Q	0000302	biological_process	response to reactive oxygen species
Q	0000303	biological_process	response to superoxide
Q	0001541	biological_process	ovarian follicle development
Q	0001819	biological_process	positive regulation of cytokine production
Q	0001890	biological_process	placenta development
Q	0001895	biological_process	retina homeostasis
Q	0001975	biological_process	response to amphetamine
Q	0002262	biological_process	myeloid cell homeostasis
Q	0004784	molecular_function	superoxide dismutase activity
Q	0005507	molecular_function	copper ion binding
Q	0005515	molecular_function	protein binding
Q	0005576	cellular_component	extracellular region
Q	0005615	cellular_component	extracellular space
Q	0005634	cellular_component	nucleus
Q	0005654	cellular_component	nucleoplasm
Q	0005737	cellular_component	cytoplasm
Q	0005739	cellular_component	mitochondrion
Q	0005758	cellular_component	mitochondrial intermembrane space
Q	0005759	cellular_component	mitochondrial matrix
Q	0005764	cellular_component	lysosome
Q	0005777	cellular_component	peroxisome
Q	0005829	cellular_component	cytosol
Q	0005886	cellular_component	plasma membrane
Q	0006749	biological_process	glutathione metabolic process
Q	0006801	biological_process	superoxide metabolic process
Q	0006879	biological_process	intracellular iron ion homeostasis
Q	0006915	biological_process	apoptotic process
Q	0006979	biological_process	response to oxidative stress
Q	0007283	biological_process	spermatogenesis
Q	0007566	biological_process	embryo implantation
Q	0007605	biological_process	sensory perception of sound
Q	0007626	biological_process	locomotory behavior
Q	0008089	biological_process	anterograde axonal transport
Q	0008090	biological_process	retrograde axonal transport
Q	0008217	biological_process	regulation of blood pressure
Q	0008270	molecular_function	zinc ion binding
Q	0008340	biological_process	determination of adult lifespan
Q	0009408	biological_process	response to heat
Q	0009410	biological_process	response to xenobiotic stimulus
Q	0010467	biological_process	gene expression
Q	0016209	molecular_function	antioxidant activity
Q	0016491	molecular_function	oxidoreductase activity
Q	0019226	biological_process	transmission of nerve impulse
Q	0019228	biological_process	neuronal action potential
Q	0019430	biological_process	removal of superoxide radicals
Q	0019899	molecular_function	enzyme binding
Q	0030141	cellular_component	secretory granule
Q	0030346	molecular_function	protein phosphatase 2B binding
Q	0031045	cellular_component	dense core granule
Q	0031267	molecular_function	small GTPase binding
Q	0031410	cellular_component	cytoplasmic vesicle
Q	0031667	biological_process	response to nutrient levels
Q	0032287	biological_process	peripheral nervous system myelin maintenance
Q	0032839	cellular_component	dendrite cytoplasm
Q	0032930	biological_process	positive regulation of superoxide anion generation
Q	0032991	cellular_component	protein-containing complex
Q	0033081	biological_process	regulation of T cell differentiation in thymus
Q	0034465	biological_process	response to carbon monoxide
Q	0034599	biological_process	cellular response to oxidative stress
Q	0035234	biological_process	ectopic germ cell programmed cell death
Q	0035865	biological_process	cellular response to potassium ion
Q	0040014	biological_process	regulation of multicellular organism growth
Q	0042542	biological_process	response to hydrogen peroxide
Q	0042554	biological_process	superoxide anion generation
Q	0042802	molecular_function	identical protein binding
Q	0042803	molecular_function	protein homodimerization activity
Q	0043025	cellular_component	neuronal cell body
Q	0043065	biological_process	positive regulation of apoptotic process
Q	0043066	biological_process	negative regulation of apoptotic process
Q	0043087	biological_process	regulation of GTPase activity
Q	0043410	biological_process	positive regulation of MAPK cascade
Q	0043524	biological_process	negative regulation of neuron apoptotic process
Q	0045471	biological_process	response to ethanol
Q	0046620	biological_process	regulation of organ growth
Q	0046688	biological_process	response to copper ion
Q	0046716	biological_process	muscle cell cellular homeostasis
Q	0046872	molecular_function	metal ion binding
Q	0048538	biological_process	thymus development
Q	0048678	biological_process	response to axon injury
Q	0050665	biological_process	hydrogen peroxide biosynthetic process
Q	0050728	biological_process	negative regulation of inflammatory response
Q	0050766	biological_process	positive regulation of phagocytosis
Q	0051087	molecular_function	protein-folding chaperone binding
Q	0051093	biological_process	negative regulation of developmental process
Q	0051881	biological_process	regulation of mitochondrial membrane potential
Q	0060047	biological_process	heart contraction
Q	0060052	biological_process	neurofilament cytoskeleton organization
Q	0060087	biological_process	relaxation of vascular associated smooth muscle
Q	0060088	biological_process	auditory receptor cell stereocilium organization
Q	0070062	cellular_component	extracellular exosome
Q	0071276	biological_process	cellular response to cadmium ion
Q	0071318	biological_process	cellular response to ATP
Q	0072593	biological_process	reactive oxygen species metabolic process
Q	0097332	biological_process	response to antipsychotic drug
Q	0099610	biological_process	action potential initiation
Q	1902177	biological_process	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
Q	1904115	cellular_component	axon cytoplasm
Q	2000242	biological_process	negative regulation of reproductive process
R	0005507	molecular_function	copper ion binding
R	0005515	molecular_function	protein binding
R	0005634	cellular_component	nucleus
R	0005737	cellular_component	cytoplasm
R	0005739	cellular_component	mitochondrion
R	0005829	cellular_component	cytosol
R	0006801	biological_process	superoxide metabolic process
R	0015035	molecular_function	protein-disulfide reductase activity
R	0016532	molecular_function	superoxide dismutase copper chaperone activity
R	0019430	biological_process	removal of superoxide radicals
R	0034599	biological_process	cellular response to oxidative stress
R	0045296	molecular_function	cadherin binding
R	0046872	molecular_function	metal ion binding
R	0051604	biological_process	protein maturation
S	0000302	biological_process	response to reactive oxygen species
S	0000303	biological_process	response to superoxide
S	0001541	biological_process	ovarian follicle development
S	0001819	biological_process	positive regulation of cytokine production
S	0001890	biological_process	placenta development
S	0001895	biological_process	retina homeostasis
S	0001975	biological_process	response to amphetamine
S	0002262	biological_process	myeloid cell homeostasis
S	0004784	molecular_function	superoxide dismutase activity
S	0005507	molecular_function	copper ion binding
S	0005515	molecular_function	protein binding
S	0005576	cellular_component	extracellular region
S	0005615	cellular_component	extracellular space
S	0005634	cellular_component	nucleus
S	0005654	cellular_component	nucleoplasm
S	0005737	cellular_component	cytoplasm
S	0005739	cellular_component	mitochondrion
S	0005758	cellular_component	mitochondrial intermembrane space
S	0005759	cellular_component	mitochondrial matrix
S	0005764	cellular_component	lysosome
S	0005777	cellular_component	peroxisome
S	0005829	cellular_component	cytosol
S	0005886	cellular_component	plasma membrane
S	0006749	biological_process	glutathione metabolic process
S	0006801	biological_process	superoxide metabolic process
S	0006879	biological_process	intracellular iron ion homeostasis
S	0006915	biological_process	apoptotic process
S	0006979	biological_process	response to oxidative stress
S	0007283	biological_process	spermatogenesis
S	0007566	biological_process	embryo implantation
S	0007605	biological_process	sensory perception of sound
S	0007626	biological_process	locomotory behavior
S	0008089	biological_process	anterograde axonal transport
S	0008090	biological_process	retrograde axonal transport
S	0008217	biological_process	regulation of blood pressure
S	0008270	molecular_function	zinc ion binding
S	0008340	biological_process	determination of adult lifespan
S	0009408	biological_process	response to heat
S	0009410	biological_process	response to xenobiotic stimulus
S	0010467	biological_process	gene expression
S	0016209	molecular_function	antioxidant activity
S	0016491	molecular_function	oxidoreductase activity
S	0019226	biological_process	transmission of nerve impulse
S	0019228	biological_process	neuronal action potential
S	0019430	biological_process	removal of superoxide radicals
S	0019899	molecular_function	enzyme binding
S	0030141	cellular_component	secretory granule
S	0030346	molecular_function	protein phosphatase 2B binding
S	0031045	cellular_component	dense core granule
S	0031267	molecular_function	small GTPase binding
S	0031410	cellular_component	cytoplasmic vesicle
S	0031667	biological_process	response to nutrient levels
S	0032287	biological_process	peripheral nervous system myelin maintenance
S	0032839	cellular_component	dendrite cytoplasm
S	0032930	biological_process	positive regulation of superoxide anion generation
S	0032991	cellular_component	protein-containing complex
S	0033081	biological_process	regulation of T cell differentiation in thymus
S	0034465	biological_process	response to carbon monoxide
S	0034599	biological_process	cellular response to oxidative stress
S	0035234	biological_process	ectopic germ cell programmed cell death
S	0035865	biological_process	cellular response to potassium ion
S	0040014	biological_process	regulation of multicellular organism growth
S	0042542	biological_process	response to hydrogen peroxide
S	0042554	biological_process	superoxide anion generation
S	0042802	molecular_function	identical protein binding
S	0042803	molecular_function	protein homodimerization activity
S	0043025	cellular_component	neuronal cell body
S	0043065	biological_process	positive regulation of apoptotic process
S	0043066	biological_process	negative regulation of apoptotic process
S	0043087	biological_process	regulation of GTPase activity
S	0043410	biological_process	positive regulation of MAPK cascade
S	0043524	biological_process	negative regulation of neuron apoptotic process
S	0045471	biological_process	response to ethanol
S	0046620	biological_process	regulation of organ growth
S	0046688	biological_process	response to copper ion
S	0046716	biological_process	muscle cell cellular homeostasis
S	0046872	molecular_function	metal ion binding
S	0048538	biological_process	thymus development
S	0048678	biological_process	response to axon injury
S	0050665	biological_process	hydrogen peroxide biosynthetic process
S	0050728	biological_process	negative regulation of inflammatory response
S	0050766	biological_process	positive regulation of phagocytosis
S	0051087	molecular_function	protein-folding chaperone binding
S	0051093	biological_process	negative regulation of developmental process
S	0051881	biological_process	regulation of mitochondrial membrane potential
S	0060047	biological_process	heart contraction
S	0060052	biological_process	neurofilament cytoskeleton organization
S	0060087	biological_process	relaxation of vascular associated smooth muscle
S	0060088	biological_process	auditory receptor cell stereocilium organization
S	0070062	cellular_component	extracellular exosome
S	0071276	biological_process	cellular response to cadmium ion
S	0071318	biological_process	cellular response to ATP
S	0072593	biological_process	reactive oxygen species metabolic process
S	0097332	biological_process	response to antipsychotic drug
S	0099610	biological_process	action potential initiation
S	1902177	biological_process	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
S	1904115	cellular_component	axon cytoplasm
S	2000242	biological_process	negative regulation of reproductive process
T	0005507	molecular_function	copper ion binding
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005737	cellular_component	cytoplasm
T	0005739	cellular_component	mitochondrion
T	0005829	cellular_component	cytosol
T	0006801	biological_process	superoxide metabolic process
T	0015035	molecular_function	protein-disulfide reductase activity
T	0016532	molecular_function	superoxide dismutase copper chaperone activity
T	0019430	biological_process	removal of superoxide radicals
T	0034599	biological_process	cellular response to oxidative stress
T	0045296	molecular_function	cadherin binding
T	0046872	molecular_function	metal ion binding
T	0051604	biological_process	protein maturation
U	0000302	biological_process	response to reactive oxygen species
U	0000303	biological_process	response to superoxide
U	0001541	biological_process	ovarian follicle development
U	0001819	biological_process	positive regulation of cytokine production
U	0001890	biological_process	placenta development
U	0001895	biological_process	retina homeostasis
U	0001975	biological_process	response to amphetamine
U	0002262	biological_process	myeloid cell homeostasis
U	0004784	molecular_function	superoxide dismutase activity
U	0005507	molecular_function	copper ion binding
U	0005515	molecular_function	protein binding
U	0005576	cellular_component	extracellular region
U	0005615	cellular_component	extracellular space
U	0005634	cellular_component	nucleus
U	0005654	cellular_component	nucleoplasm
U	0005737	cellular_component	cytoplasm
U	0005739	cellular_component	mitochondrion
U	0005758	cellular_component	mitochondrial intermembrane space
U	0005759	cellular_component	mitochondrial matrix
U	0005764	cellular_component	lysosome
U	0005777	cellular_component	peroxisome
U	0005829	cellular_component	cytosol
U	0005886	cellular_component	plasma membrane
U	0006749	biological_process	glutathione metabolic process
U	0006801	biological_process	superoxide metabolic process
U	0006879	biological_process	intracellular iron ion homeostasis
U	0006915	biological_process	apoptotic process
U	0006979	biological_process	response to oxidative stress
U	0007283	biological_process	spermatogenesis
U	0007566	biological_process	embryo implantation
U	0007605	biological_process	sensory perception of sound
U	0007626	biological_process	locomotory behavior
U	0008089	biological_process	anterograde axonal transport
U	0008090	biological_process	retrograde axonal transport
U	0008217	biological_process	regulation of blood pressure
U	0008270	molecular_function	zinc ion binding
U	0008340	biological_process	determination of adult lifespan
U	0009408	biological_process	response to heat
U	0009410	biological_process	response to xenobiotic stimulus
U	0010467	biological_process	gene expression
U	0016209	molecular_function	antioxidant activity
U	0016491	molecular_function	oxidoreductase activity
U	0019226	biological_process	transmission of nerve impulse
U	0019228	biological_process	neuronal action potential
U	0019430	biological_process	removal of superoxide radicals
U	0019899	molecular_function	enzyme binding
U	0030141	cellular_component	secretory granule
U	0030346	molecular_function	protein phosphatase 2B binding
U	0031045	cellular_component	dense core granule
U	0031267	molecular_function	small GTPase binding
U	0031410	cellular_component	cytoplasmic vesicle
U	0031667	biological_process	response to nutrient levels
U	0032287	biological_process	peripheral nervous system myelin maintenance
U	0032839	cellular_component	dendrite cytoplasm
U	0032930	biological_process	positive regulation of superoxide anion generation
U	0032991	cellular_component	protein-containing complex
U	0033081	biological_process	regulation of T cell differentiation in thymus
U	0034465	biological_process	response to carbon monoxide
U	0034599	biological_process	cellular response to oxidative stress
U	0035234	biological_process	ectopic germ cell programmed cell death
U	0035865	biological_process	cellular response to potassium ion
U	0040014	biological_process	regulation of multicellular organism growth
U	0042542	biological_process	response to hydrogen peroxide
U	0042554	biological_process	superoxide anion generation
U	0042802	molecular_function	identical protein binding
U	0042803	molecular_function	protein homodimerization activity
U	0043025	cellular_component	neuronal cell body
U	0043065	biological_process	positive regulation of apoptotic process
U	0043066	biological_process	negative regulation of apoptotic process
U	0043087	biological_process	regulation of GTPase activity
U	0043410	biological_process	positive regulation of MAPK cascade
U	0043524	biological_process	negative regulation of neuron apoptotic process
U	0045471	biological_process	response to ethanol
U	0046620	biological_process	regulation of organ growth
U	0046688	biological_process	response to copper ion
U	0046716	biological_process	muscle cell cellular homeostasis
U	0046872	molecular_function	metal ion binding
U	0048538	biological_process	thymus development
U	0048678	biological_process	response to axon injury
U	0050665	biological_process	hydrogen peroxide biosynthetic process
U	0050728	biological_process	negative regulation of inflammatory response
U	0050766	biological_process	positive regulation of phagocytosis
U	0051087	molecular_function	protein-folding chaperone binding
U	0051093	biological_process	negative regulation of developmental process
U	0051881	biological_process	regulation of mitochondrial membrane potential
U	0060047	biological_process	heart contraction
U	0060052	biological_process	neurofilament cytoskeleton organization
U	0060087	biological_process	relaxation of vascular associated smooth muscle
U	0060088	biological_process	auditory receptor cell stereocilium organization
U	0070062	cellular_component	extracellular exosome
U	0071276	biological_process	cellular response to cadmium ion
U	0071318	biological_process	cellular response to ATP
U	0072593	biological_process	reactive oxygen species metabolic process
U	0097332	biological_process	response to antipsychotic drug
U	0099610	biological_process	action potential initiation
U	1902177	biological_process	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
U	1904115	cellular_component	axon cytoplasm
U	2000242	biological_process	negative regulation of reproductive process
V	0005507	molecular_function	copper ion binding
V	0005515	molecular_function	protein binding
V	0005634	cellular_component	nucleus
V	0005737	cellular_component	cytoplasm
V	0005739	cellular_component	mitochondrion
V	0005829	cellular_component	cytosol
V	0006801	biological_process	superoxide metabolic process
V	0015035	molecular_function	protein-disulfide reductase activity
V	0016532	molecular_function	superoxide dismutase copper chaperone activity
V	0019430	biological_process	removal of superoxide radicals
V	0034599	biological_process	cellular response to oxidative stress
V	0045296	molecular_function	cadherin binding
V	0046872	molecular_function	metal ion binding
V	0051604	biological_process	protein maturation
W	0000302	biological_process	response to reactive oxygen species
W	0000303	biological_process	response to superoxide
W	0001541	biological_process	ovarian follicle development
W	0001819	biological_process	positive regulation of cytokine production
W	0001890	biological_process	placenta development
W	0001895	biological_process	retina homeostasis
W	0001975	biological_process	response to amphetamine
W	0002262	biological_process	myeloid cell homeostasis
W	0004784	molecular_function	superoxide dismutase activity
W	0005507	molecular_function	copper ion binding
W	0005515	molecular_function	protein binding
W	0005576	cellular_component	extracellular region
W	0005615	cellular_component	extracellular space
W	0005634	cellular_component	nucleus
W	0005654	cellular_component	nucleoplasm
W	0005737	cellular_component	cytoplasm
W	0005739	cellular_component	mitochondrion
W	0005758	cellular_component	mitochondrial intermembrane space
W	0005759	cellular_component	mitochondrial matrix
W	0005764	cellular_component	lysosome
W	0005777	cellular_component	peroxisome
W	0005829	cellular_component	cytosol
W	0005886	cellular_component	plasma membrane
W	0006749	biological_process	glutathione metabolic process
W	0006801	biological_process	superoxide metabolic process
W	0006879	biological_process	intracellular iron ion homeostasis
W	0006915	biological_process	apoptotic process
W	0006979	biological_process	response to oxidative stress
W	0007283	biological_process	spermatogenesis
W	0007566	biological_process	embryo implantation
W	0007605	biological_process	sensory perception of sound
W	0007626	biological_process	locomotory behavior
W	0008089	biological_process	anterograde axonal transport
W	0008090	biological_process	retrograde axonal transport
W	0008217	biological_process	regulation of blood pressure
W	0008270	molecular_function	zinc ion binding
W	0008340	biological_process	determination of adult lifespan
W	0009408	biological_process	response to heat
W	0009410	biological_process	response to xenobiotic stimulus
W	0010467	biological_process	gene expression
W	0016209	molecular_function	antioxidant activity
W	0016491	molecular_function	oxidoreductase activity
W	0019226	biological_process	transmission of nerve impulse
W	0019228	biological_process	neuronal action potential
W	0019430	biological_process	removal of superoxide radicals
W	0019899	molecular_function	enzyme binding
W	0030141	cellular_component	secretory granule
W	0030346	molecular_function	protein phosphatase 2B binding
W	0031045	cellular_component	dense core granule
W	0031267	molecular_function	small GTPase binding
W	0031410	cellular_component	cytoplasmic vesicle
W	0031667	biological_process	response to nutrient levels
W	0032287	biological_process	peripheral nervous system myelin maintenance
W	0032839	cellular_component	dendrite cytoplasm
W	0032930	biological_process	positive regulation of superoxide anion generation
W	0032991	cellular_component	protein-containing complex
W	0033081	biological_process	regulation of T cell differentiation in thymus
W	0034465	biological_process	response to carbon monoxide
W	0034599	biological_process	cellular response to oxidative stress
W	0035234	biological_process	ectopic germ cell programmed cell death
W	0035865	biological_process	cellular response to potassium ion
W	0040014	biological_process	regulation of multicellular organism growth
W	0042542	biological_process	response to hydrogen peroxide
W	0042554	biological_process	superoxide anion generation
W	0042802	molecular_function	identical protein binding
W	0042803	molecular_function	protein homodimerization activity
W	0043025	cellular_component	neuronal cell body
W	0043065	biological_process	positive regulation of apoptotic process
W	0043066	biological_process	negative regulation of apoptotic process
W	0043087	biological_process	regulation of GTPase activity
W	0043410	biological_process	positive regulation of MAPK cascade
W	0043524	biological_process	negative regulation of neuron apoptotic process
W	0045471	biological_process	response to ethanol
W	0046620	biological_process	regulation of organ growth
W	0046688	biological_process	response to copper ion
W	0046716	biological_process	muscle cell cellular homeostasis
W	0046872	molecular_function	metal ion binding
W	0048538	biological_process	thymus development
W	0048678	biological_process	response to axon injury
W	0050665	biological_process	hydrogen peroxide biosynthetic process
W	0050728	biological_process	negative regulation of inflammatory response
W	0050766	biological_process	positive regulation of phagocytosis
W	0051087	molecular_function	protein-folding chaperone binding
W	0051093	biological_process	negative regulation of developmental process
W	0051881	biological_process	regulation of mitochondrial membrane potential
W	0060047	biological_process	heart contraction
W	0060052	biological_process	neurofilament cytoskeleton organization
W	0060087	biological_process	relaxation of vascular associated smooth muscle
W	0060088	biological_process	auditory receptor cell stereocilium organization
W	0070062	cellular_component	extracellular exosome
W	0071276	biological_process	cellular response to cadmium ion
W	0071318	biological_process	cellular response to ATP
W	0072593	biological_process	reactive oxygen species metabolic process
W	0097332	biological_process	response to antipsychotic drug
W	0099610	biological_process	action potential initiation
W	1902177	biological_process	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
W	1904115	cellular_component	axon cytoplasm
W	2000242	biological_process	negative regulation of reproductive process
X	0005507	molecular_function	copper ion binding
X	0005515	molecular_function	protein binding
X	0005634	cellular_component	nucleus
X	0005737	cellular_component	cytoplasm
X	0005739	cellular_component	mitochondrion
X	0005829	cellular_component	cytosol
X	0006801	biological_process	superoxide metabolic process
X	0015035	molecular_function	protein-disulfide reductase activity
X	0016532	molecular_function	superoxide dismutase copper chaperone activity
X	0019430	biological_process	removal of superoxide radicals
X	0034599	biological_process	cellular response to oxidative stress
X	0045296	molecular_function	cadherin binding
X	0046872	molecular_function	metal ion binding
X	0051604	biological_process	protein maturation

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 201

Chain	Residue
A	HIS63
A	HIS71
A	HIS80
A	ASP83

---

site_id	AC2
Number of Residues	3
Details	binding site for residue PPI A 202

Chain	Residue
A	ASN26
A	HIS110
J	GLU186

---

site_id	AC3
Number of Residues	4
Details	binding site for residue PPI A 203

Chain	Residue
E	ALA89
J	ASP160
A	GLU24
E	GLU40

---

site_id	AC4
Number of Residues	5
Details	binding site for residue GOL A 204

Chain	Residue
A	GLU40
A	ASP90
A	LYS91
D	ASP160
E	GLU24

---

site_id	AC5
Number of Residues	4
Details	binding site for residue ZN B 400

Chain	Residue
B	HIS147
B	HIS155
B	HIS164
B	ASP167

---

site_id	AC6
Number of Residues	5
Details	binding site for residue ZN C 201

Chain	Residue
C	HIS63
C	HIS71
C	HIS80
C	ASP83
C	LYS136

---

site_id	AC7
Number of Residues	4
Details	binding site for residue ZN D 400

Chain	Residue
D	HIS147
D	HIS155
D	HIS164
D	ASP167

---

site_id	AC8
Number of Residues	5
Details	binding site for residue ZN E 201

Chain	Residue
E	HIS63
E	HIS71
E	HIS80
E	ASP83
E	LYS136

---

site_id	AC9
Number of Residues	4
Details	binding site for residue ZN F 400

Chain	Residue
F	HIS147
F	HIS155
F	HIS164
F	ASP167

---

site_id	AD1
Number of Residues	4
Details	binding site for residue ZN G 201

Chain	Residue
G	HIS63
G	HIS71
G	HIS80
G	ASP83

---

site_id	AD2
Number of Residues	4
Details	binding site for residue ZN H 400

Chain	Residue
H	HIS147
H	HIS155
H	HIS164
H	ASP167

---

site_id	AD3
Number of Residues	5
Details	binding site for residue ZN I 201

Chain	Residue
I	HIS63
I	HIS71
I	HIS80
I	ASP83
I	LYS136

---

site_id	AD4
Number of Residues	1
Details	binding site for residue PPI I 202

Chain	Residue
I	TRP32

---

site_id	AD5
Number of Residues	4
Details	binding site for residue ZN J 400

Chain	Residue
J	HIS147
J	HIS155
J	HIS164
J	ASP167

---

site_id	AD6
Number of Residues	5
Details	binding site for residue ZN K 201

Chain	Residue
K	HIS63
K	HIS71
K	HIS80
K	ASP83
K	LYS136

---

site_id	AD7
Number of Residues	6
Details	binding site for residue PPI K 202

Chain	Residue
G	GLU24
K	GLU40
K	ASP90
N	GLN159
N	ASP160
N	ARG209

---

site_id	AD8
Number of Residues	3
Details	binding site for residue PPI K 203

Chain	Residue
K	ASP90
K	ASP92
N	ASP162

---

site_id	AD9
Number of Residues	4
Details	binding site for residue ZN L 400

Chain	Residue
L	HIS147
L	HIS155
L	HIS164
L	ASP167

---

site_id	AE1
Number of Residues	4
Details	binding site for residue ZN M 201

Chain	Residue
M	HIS63
M	HIS71
M	HIS80
M	ASP83

---

site_id	AE2
Number of Residues	4
Details	binding site for residue ZN N 400

Chain	Residue
N	HIS147
N	HIS155
N	HIS164
N	ASP167

---

site_id	AE3
Number of Residues	4
Details	binding site for residue ZN O 201

Chain	Residue
O	HIS63
O	HIS71
O	HIS80
O	ASP83

---

site_id	AE4
Number of Residues	4
Details	binding site for residue ZN P 400

Chain	Residue
P	HIS147
P	HIS155
P	HIS164
P	ASP167

---

site_id	AE5
Number of Residues	4
Details	binding site for residue ZN Q 201

Chain	Residue
Q	HIS63
Q	HIS71
Q	HIS80
Q	ASP83

---

site_id	AE6
Number of Residues	4
Details	binding site for residue ZN R 301

Chain	Residue
R	HIS147
R	HIS155
R	HIS164
R	ASP167

---

site_id	AE7
Number of Residues	7
Details	binding site for residue PPI R 302

Chain	Residue
O	ASP90
O	LYS91
R	GLN159
R	ASP160
S	LYS23
S	GLU24
O	GLU40

---

site_id	AE8
Number of Residues	5
Details	binding site for residue ZN S 201

Chain	Residue
S	HIS63
S	HIS71
S	HIS80
S	ASP83
S	LYS136

---

site_id	AE9
Number of Residues	4
Details	binding site for residue ZN T 400

Chain	Residue
T	HIS147
T	HIS155
T	HIS164
T	ASP167

---

site_id	AF1
Number of Residues	4
Details	binding site for residue ZN U 201

Chain	Residue
U	HIS63
U	HIS71
U	HIS80
U	ASP83

---

site_id	AF2
Number of Residues	4
Details	binding site for residue ZN V 400

Chain	Residue
V	HIS147
V	HIS155
V	HIS164
V	ASP167

---

site_id	AF3
Number of Residues	4
Details	binding site for residue ZN W 201

Chain	Residue
W	HIS63
W	HIS71
W	HIS80
W	ASP83

---

site_id	AF4
Number of Residues	4
Details	binding site for residue ZN X 400

Chain	Residue
X	HIS147
X	HIS155
X	HIS164
X	ASP167

---

Functional Information from PROSITE/UniProt

site_id	PS00087
Number of Residues	11
Details	SOD_CU_ZN_1 Copper/Zinc superoxide dismutase signature 1. GFHVHEfGDnT

Chain	Residue	Details
A	GLY44-THR54

---

site_id	PS00332
Number of Residues	12
Details	SOD_CU_ZN_2 Copper/Zinc superoxide dismutase signature 2. GNSGeRlACgiI

Chain	Residue	Details
B	GLY219-ILE230

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	36
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12963370","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17548825","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	48
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20727846","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"PubMed","id":"1463506","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7002610","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25944712","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	35
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P08228","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	12
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	12
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	12
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P07632","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	12
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P08228","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	12
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"PubMed","id":"24140062","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	12
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P08228","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	12
Details	Lipidation: {"description":"S-palmitoyl cysteine","evidences":[{"source":"PubMed","id":"22496122","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	24
Details	Cross-link: {"description":"1-(tryptophan-3-yl)-tryptophan (Trp-Trp) (interchain with W-33)","evidences":[{"source":"PubMed","id":"20600836","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	567
Details	Domain: {"description":"HMA","evidences":[{"source":"PROSITE-ProRule","id":"PRU00280","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	1606
Details	Region: {"description":"Superoxide dismutase-like"}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	21
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00280","evidenceCode":"ECO:0000255"},{"source":"PDB","id":"2RSQ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	48
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10677207","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1DO5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	52
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"20154138","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---