6FP6
Complex of human Cu,Zn SOD1 with the human copper chaperone for SOD1 in a compact conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G, I... (A, C, E, G, I...) | Superoxide dismutase [Cu-Zn] | polymer | 153 | 15763.4 | 12 | UniProt (P00441) Pfam (PF00080) | Homo sapiens (Human) | Superoxide dismutase 1,hSod1 |
| 2 | B, D, F, H, J... (B, D, F, H, J...) | Copper chaperone for superoxide dismutase | polymer | 274 | 28977.4 | 12 | UniProt (O14618) Pfam (PF00403) Pfam (PF00080) | Homo sapiens (Human) | Superoxide dismutase copper chaperone |
| 3 | AB, BB, CA, CB, DA... (V, W, B, X, C...) | ZINC ION | non-polymer | 65.4 | 24 | Chemie (ZN) | |||
| 4 | AA, KA, NA, OA, WA... (A, I, K, R) | PROPANOIC ACID | non-polymer | 74.1 | 6 | Chemie (PPI) | |||
| 5 | BA (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | DB, EB, FB, GB, HB... (A, B, C, D, E...) | water | water | 18.0 | 75 | Chemie (HOH) |
Sequence modifications
A, C, E, G, I, K, M, O, Q, S, U, W: 1 - 153 (UniProt: P00441)
B, D, F, H, J, L, N, P, R, T, V, X: 1 - 274 (UniProt: O14618)
| PDB | External Database | Details |
|---|---|---|
| Ala 57 | Cys 58 | engineered mutation |
| Ala 146 | Cys 147 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 12 | Cys 12 | engineered mutation |
| Ala 22 | Cys 22 | engineered mutation |
| Ala 25 | Cys 25 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 24 |
| Total formula weight | 536890.0 | |
| Non-Polymers* | Number of molecules | 31 |
| Total formula weight | 2106.4 | |
| All* | Total formula weight | 538996.4 |
