6FI8

Crystal structure of the IS608 transposase in complex with left end 29-mer DNA hairpin and a 6-mer DNA representing the intact target site: pre-cleavage target capture complex

Summary for 6FI8

• Entry DOI: 10.2210/pdb6fi8/pdb
• Descriptor: Putative transposase, DNA 29-MER (LE29), DNA 6-MER (T6'), ... (5 entities in total)
• Functional Keywords: dna-binding protein, protein-dna complex, huh motif, dna stem loop, transposition, tnpa transposase, target capture complex, ishp608, dna binding protein
• Biological source: Helicobacter pylori (Campylobacter pylori); More
• Total number of polymer chains: 12
• Total formula weight: 117018.87

Authors

Morero, N.R.,Barabas, O. (deposition date: 2018-01-17, release date: 2018-03-28, Last modification date: 2024-01-17)

• Primary citation: Morero, N.R.,Zuliani, C.,Kumar, B.,Bebel, A.,Okamoto, S.,Guynet, C.,Hickman, A.B.,Chandler, M.,Dyda, F.,Barabas, O.; Targeting IS608 transposon integration to highly specific sequences by structure-based transposon engineering.; Nucleic Acids Res., 46:4152-4163, 2018; PubMed: 29635476; DOI: 10.1093/nar/gky235

Experimental method

X-RAY DIFFRACTION (2.598 Å)